Department of General Surgery, KTO Karatay University, Medical Faculty, Konya, Turkey.
Department of General Surgery, Konya Training and Research Hospital, Konya, Turkey.
Med Princ Pract. 2021;30(5):455-461. doi: 10.1159/000516903. Epub 2021 Apr 29.
The most important cause of posttreatment recurrence of pilonidal sinus disease (PSD) is the reentry of hair into the skin. The study aimed to investigate the effect of hair removal and its duration on the prevention of recurrence after crystallized phenol treatment.
Patients with PSD who were treated with crystallized phenol treatment were evaluated. Hair in the sacrococcygeal area was removed with depilatory cream before every crystallized phenol procedure, during the treatment, and after treatment once a month for 6 years. Of 1,016 patients, 735 were contacted by telephone or e-mail regarding the frequency of sacrococcygeal hair removal and recurrence. Demographic and sinus features and crystallized phenol application data of patients treated with crystallized phenol for PSD, as well as recurrences were retrospectively assessed.
The mean follow-up time was 46.23 ± 33 (range, 11-240) months, with 139 (18.9%) patients experiencing recurrence. Patients who underwent hair removal experienced significantly less recurrence than those who did not (p = 0.003, odds ratio [OR]: 0.54 [95% CI: 0.36-0.82]). The OR of recurrence decreased by 0.8% every month as the hair removal time increased (OR: 0.992, 95% CI: 0.985-1.000, p = 0.049). The cutoff value for sensitivity was 0.636, specificity 0.466, and area under the curve 0.562 in hair removal procedures that lasted for over 30 months.
Regular hair removal during, and at least 30 months after, crystallized phenol treatment reduced recurrences in patients with PSD.
藏毛窦疾病（PSD）治疗后复发的最重要原因是毛发再次进入皮肤。本研究旨在探讨脱毛及其持续时间对结晶苯酚治疗后复发的预防效果。
评估接受结晶苯酚治疗的 PSD 患者。在每次结晶苯酚治疗前、治疗期间以及治疗后每月一次（共 6 年）使用脱毛霜去除骶尾部区域的毛发。1016 例患者中，通过电话或电子邮件联系了 735 例，了解骶尾部毛发去除和复发的频率。回顾性评估接受结晶苯酚治疗 PSD 的患者的人口统计学和窦特征以及结晶苯酚应用数据，以及复发情况。
平均随访时间为 46.23±33 个月（范围：11-240 个月），139 例（18.9%）患者复发。与未行脱毛的患者相比，行脱毛的患者复发率显著降低（p=0.003，优势比[OR]：0.54[95%可信区间：0.36-0.82]）。随着脱毛时间的增加，复发的 OR 每月降低 0.8%（OR：0.992，95%可信区间：0.985-1.000，p=0.049）。脱毛持续时间超过 30 个月的敏感度为 0.636，特异性为 0.466，曲线下面积为 0.562。
在结晶苯酚治疗期间和治疗后至少 30 个月进行定期脱毛可降低 PSD 患者的复发率。
