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麻醉山羊腮腺和下颌下腺唾液分泌的比较研究:毛果芸香碱的作用

A comparative study of salivary secretion by parotid and mandibular glands of anaesthetized Capra hircus: effect of pilocarpine.

作者信息

Castellano C, Moreno M, Raggi L A, Martinez de Victoria E, Mataix F J

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1986;85(2):291-6. doi: 10.1016/0742-8413(86)90196-9.

Abstract

A study was made of basal secretion and the effect of the infusion of pilocarpine on the flow and composition of saliva in the parotid and mandibular glands of the anaesthetized lactating goat. In the parotid gland there was a basal flow (1.6 +/- 0.29 microliter/min) which was not present in the mandibular gland. There is a statistically significant dose-effect relationship between pilocarpine and salivary flow in both glands. Salival composition and its variation with respect to the flow of saliva did not conform to either of the two glands to an exclusive monogastric or ruminant model.

摘要

对麻醉的泌乳山羊腮腺和下颌下腺的基础分泌以及毛果芸香碱输注对唾液流量和成分的影响进行了研究。腮腺存在基础流量(1.6±0.29微升/分钟),而下颌下腺不存在。在两个腺体中,毛果芸香碱与唾液流量之间存在统计学上显著的剂量效应关系。唾液成分及其随唾液流量的变化并不完全符合单胃动物或反刍动物这两种腺体模型中的任何一种。

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