Bianchetti G, Thiercelin J F, Thenot J P
Eur J Clin Pharmacol. 1986;31(2):231-3. doi: 10.1007/BF00606665.
The pharmacokinetics of betaxolol was studied in 8 middle-aged (40-60 years) subjects after oral (20 mg) and intravenous (10 mg) administration. The principal parameters were almost identical to those observed in young healthy volunteers. The recommended therapeutic regimen, a single daily dose of 20 mg, appears well suited for middle aged, hypertensive patients.
在8名中年(40 - 60岁)受试者口服(20毫克)和静脉注射(10毫克)倍他洛尔后,对其药代动力学进行了研究。主要参数与在年轻健康志愿者中观察到的几乎相同。推荐的治疗方案为每日单次剂量20毫克,似乎非常适合中年高血压患者。