Suppr超能文献

美国安全网中经皮冠状动脉介入治疗的住院治疗结果:来自 NCDR Cath-PCI 登记处的见解。

In-Hospital Outcomes of Percutaneous Coronary Intervention in America's Safety Net: Insights From the NCDR Cath-PCI Registry.

机构信息

University of California, San Francisco, Fresno, California.

Saint Luke's Mid-America Heart Institute, Kansas City, Missouri; University of Missouri-Kansas City, Kansas City, Missouri.

出版信息

JACC Cardiovasc Interv. 2017 Aug 14;10(15):1475-1485. doi: 10.1016/j.jcin.2017.05.042.

Abstract

OBJECTIVES

This study compared risk-adjusted percutaneous coronary intervention (PCI) outcomes of safety-net hospitals (SNHs) and non-SNHs.

BACKGROUND

Although risk adjustment is used to compare hospitals, SNHs treat a disproportionate share of uninsured and underinsured patients, who may have unmeasured risk factors, limited health care access, and poorer outcomes than patients treated at non-SNHs.

METHODS

Using the National Cardiovascular Data Registry CathPCI Registry from 2009 to 2015, we analyzed 3,746,961 patients who underwent PCI at 282 SNHs (hospitals where ≥10% of PCI patients were uninsured) and 1,134 non-SNHs. The relationship between SNH status and risk-adjusted outcomes was assessed.

RESULTS

SNHs were more likely to be lower volume, rural hospitals located in the southern states. Patients treated at SNHs were younger (63 vs. 65 years), more often nonwhite (17% vs. 12%), smokers (33% vs. 26%), and more likely to be admitted through the emergency department (48% vs. 38%) and to have an ST-segment elevation myocardial infarction (20% vs. 14%) than non-SNHs (all p < 0.001). Patients undergoing PCI at SNHs had higher risk-adjusted in-hospital mortality (odds ratio: 1.23; 95% confidence interval: 1.17 to 1.32; p < 0.001), although the absolute risk difference between groups was small (0.4%). Risk-adjusted bleeding (odds ratio: 1.05; 95% confidence interval: 1.00 to 1.12; p = 0.062) and acute kidney injury rates (odds ratio: 1.01; 95% confidence interval: 0.96 to 1.07; p = 0.51) were similar.

CONCLUSIONS

Despite treating a higher proportion of uninsured patients with more acute presentations, risk-adjusted PCI-related in-hospital mortality of SNHs is only marginally higher (4 additional deaths per 1,000 PCI cases) than non-SNHs, whereas risk-adjusted bleeding and acute kidney injury rates are comparable.

摘要

目的

本研究比较了安全网医院(SNH)和非 SNH 的经皮冠状动脉介入治疗(PCI)风险调整结局。

背景

尽管风险调整用于比较医院,但 SNH 治疗的无保险和保险不足的患者比例不成比例,这些患者可能存在未测量的风险因素、有限的医疗保健机会和比非 SNH 治疗的患者更差的结局。

方法

使用 2009 年至 2015 年国家心血管数据登记处 CathPCI 登记处,我们分析了在 282 家 SNH(接受 PCI 的患者中≥10%无保险)和 1134 家非 SNH 接受 PCI 的 3746961 名患者。评估 SNH 状态与风险调整结局之间的关系。

结果

SNH 更可能是较低容量、位于南部各州的农村医院。在 SNH 接受治疗的患者年龄更小(63 岁 vs. 65 岁),非白人(17% vs. 12%)、吸烟者(33% vs. 26%)的比例更高,更有可能通过急诊就诊(48% vs. 38%),且更有可能患有 ST 段抬高型心肌梗死(20% vs. 14%),而非 SNH(所有 p<0.001)。在 SNH 接受 PCI 的患者的风险调整院内死亡率较高(优势比:1.23;95%置信区间:1.17 至 1.32;p<0.001),尽管两组之间的绝对风险差异较小(0.4%)。风险调整后的出血(优势比:1.05;95%置信区间:1.00 至 1.12;p=0.062)和急性肾损伤发生率(优势比:1.01;95%置信区间:0.96 至 1.07;p=0.51)相似。

结论

尽管 SNH 治疗的无保险患者比例更高,且临床表现更急性,但风险调整后的 PCI 相关院内死亡率仅略高于非 SNH(每 1000 例 PCI 病例增加 4 例死亡),而风险调整后的出血和急性肾损伤发生率相似。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验