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美国65岁以上患者经皮冠状动脉介入治疗的种族差异与预后:一项系统评价

Racial Disparities and Outcomes of Percutaneous Coronary Interventions in Patients Above 65 Years in America: A Systematic Review.

作者信息

Olanisa Olawale O, Parab Panah, Chaudhary Priti, Mukhtar Sonia, Moradi Ali, Kodali Athri, Okoye Chiugo, Klein Dhadon, Mohamoud Iman, Mohammed Lubna

机构信息

Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.

Internal Medicine, Lahore Medical and Dental College, Lahore, PAK.

出版信息

Cureus. 2023 Jul 25;15(7):e42457. doi: 10.7759/cureus.42457. eCollection 2023 Jul.

Abstract

This systematic review aims to examine the racial disparities and outcomes of percutaneous coronary interventions (PCIs) in patients above 65 years in America. The review follows the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines 2020 and includes a comprehensive search strategy, study selection, data extraction, and quality assessment. The search strategy identified 10 relevant articles that were included in the review. The findings indicate that racial disparities exist in access to PCI, door-to-balloon (DTB) time, procedure utilization, and outcomes among elderly patients. African American and Hispanic patients were found to experience longer door-to-balloon time and lower rates of PCI utilization compared to White patients. Moreover, racial and ethnic minorities had worse clinical outcomes, including higher mortality rates and increased risk of major adverse cardiovascular events. The review also highlights the impact of Medicaid expansion on reducing disparities in access, treatment, and outcomes for patients with acute myocardial infarction (AMI). However, limitations in data availability and representation of racial and ethnic minorities in clinical trials were identified. The discussion section provides a robust analysis of the findings, exploring potential underlying factors contributing to the observed disparities. The review concludes that addressing racial disparities in PCI outcomes among elderly patients is crucial for achieving equitable healthcare delivery and improving cardiovascular health outcomes in America.

摘要

本系统评价旨在研究美国65岁以上患者经皮冠状动脉介入治疗(PCI)中的种族差异及治疗结果。该评价遵循2020年系统评价与Meta分析的首选报告项目(PRISMA)指南,包括全面的检索策略、研究选择、数据提取和质量评估。检索策略确定了10篇相关文章纳入本评价。研究结果表明,老年患者在获得PCI治疗、门球时间(DTB)、治疗应用及治疗结果方面存在种族差异。与白人患者相比,非裔美国人和西班牙裔患者的门球时间更长,PCI利用率更低。此外,少数族裔的临床结果更差,包括更高的死亡率和主要不良心血管事件风险增加。该评价还强调了医疗补助扩大对减少急性心肌梗死(AMI)患者在获得治疗、治疗及治疗结果方面的差异的影响。然而,研究发现了数据可用性以及临床试验中少数族裔代表性方面的局限性。讨论部分对研究结果进行了深入分析,探讨了导致观察到的差异的潜在因素。该评价得出结论,解决老年患者PCI治疗结果中的种族差异对于在美国实现公平的医疗服务提供和改善心血管健康结果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/10450101/9bc69907a62e/cureus-0015-00000042457-i01.jpg

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