Al-Osail Aisha M, Al-Saif Hind S, Al-Hajri Mashail M, Al-Zuhair Hajer M, Al-Abdulhadi Deemah A, Al-Osail Emad M, Al-Hajri Sarah M
Department of Internal Medicine, Imam Abdulrahman Bin Faisal University, Prince Saud bin Fahd Street, Khobar, KSA.
Department of Radiology, Imam Abdulrahman Bin Faisal University, Prince Saud bin Fahd Street, Khobar, KSA.
Gulf J Oncolog. 2017 May;1(24):61-65.
Pulmonary manifestation of Hodgkin's lymphoma is common, and recently, single and/or multiple lung cavities with air-fluid levels has been reported as a primary manifestation of Hodgkin's lymphoma. However, the unusual presentation of the lung cavity itself has not been previously reported for Hodgkin's lymphoma, especially as the first presentation of the disease.
We report a 16-year-old male who presented to the emergency department with chief complaints of fever, unintentional 10-kilogram weight loss, a productive cough and pulmonary cavity for investigation. The patient's CT scan indicated multiloculated cavity lesions in the middle lobe with an air-fluid level and multiple enlarged mediastinal lymph nodes, which have not been previously reported as a primary presentation for Hodgkin's lymphoma or in the histopathology of the nodular sclerosing type of classical Hodgkin's lymphoma.
Pulmonary manifestation of Hodgkin's lymphoma has already been reported and must be part of the differential diagnosis of lung cavity lesions, even if the likelihood is low based on previous reports, especially in younger individuals. Multiloculated lung cavities can be the first presentation of Hodgkin's lymphoma.
霍奇金淋巴瘤的肺部表现较为常见,近来,有报道称单发性和/或多发性伴有气液平面的肺空洞是霍奇金淋巴瘤的主要表现。然而,此前尚未有关于霍奇金淋巴瘤肺空洞本身异常表现的报道,尤其是作为该疾病的首发表现。
我们报告一名16岁男性,因发热、体重意外减轻10公斤、咳痰及肺部空洞前往急诊科就诊以进行检查。患者的CT扫描显示中叶有多个分隔的空洞性病变,伴有气液平面,以及多个纵隔淋巴结肿大,此前这些表现尚未作为霍奇金淋巴瘤的首发表现或经典型结节硬化型霍奇金淋巴瘤的组织病理学表现被报道过。
霍奇金淋巴瘤的肺部表现已有报道,即使根据既往报道其可能性较低,尤其是在年轻个体中,它也必须成为肺空洞病变鉴别诊断的一部分。多发性肺空洞可能是霍奇金淋巴瘤的首发表现。