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原发性肺霍奇金淋巴瘤及2006年以来的文献综述

Primary pulmonary Hodgkin's lymphoma and a review of the literature since 2006.

作者信息

Cooksley Nathania, Judge Daniel James, Brown James

机构信息

Department of Thoracic Medicine, Cairns Hospital, Cairns, Queensland, Australia.

出版信息

BMJ Case Rep. 2014 Apr 7;2014:bcr2014204020. doi: 10.1136/bcr-2014-204020.

Abstract

A 28-year-old woman of Laotian origin presented with dry cough, fevers, night sweats and weight loss over the preceding 6 weeks. Radiological investigations revealed large complex cavitary lesions in the middle and lower lobes of the right lung, with no mediastinal lymph node enlargement. Bronchoscopic investigations did not yield a diagnosis. CT-guided fine-needle aspiration raised the possibility of Langerhans cell histiocytosis. Open lung biopsy initially supported this, but eventually a microscopic and immunohistochemical diagnosis of Hodgkin's lymphoma was made. The final diagnosis was primary pulmonary Hodgkin's lymphoma. We present a new case as well as a literature review of reported cases published since 2006.

摘要

一名28岁的老挝裔女性在过去6周内出现干咳、发热、盗汗和体重减轻症状。影像学检查显示右肺中叶和下叶有巨大的复杂性空洞性病变,纵隔淋巴结无肿大。支气管镜检查未得出诊断结果。CT引导下细针穿刺活检提示朗格汉斯细胞组织细胞增多症的可能性。开胸肺活检最初支持这一诊断,但最终经显微镜检查和免疫组化诊断为霍奇金淋巴瘤。最终诊断为原发性肺霍奇金淋巴瘤。我们报告了一例新病例,并对2006年以来发表的报告病例进行了文献综述。

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