Merté H J
Klin Monbl Augenheilkd. 1986 Nov;189(5):396-7.
A study was conducted to investigate the influence of a vasodilating beta receptor blocking substance on IOP in eyes with open-angle glaucoma. The study proceeded from the hypothesis that throttling of the production of aqueous humor by beta blockers and reduction of intraocular pressure is caused by vasoconstriction of the afferent vessels. The authors found that the degree of reduction of intraocular pressure corresponded to the effect of beta blockers routinely applied in glaucoma therapy. However, the duration of the effect was shorter. The above-mentioned hypothesis would thus seem to be disproved.
开展了一项研究,以调查一种血管舒张性β受体阻断物质对开角型青光眼患者眼压的影响。该研究基于这样一种假设,即β受体阻滞剂对房水生成的抑制作用以及眼压降低是由传入血管的血管收缩引起的。作者发现,眼压降低的程度与青光眼治疗中常规使用的β受体阻滞剂的效果相当。然而,这种效果的持续时间较短。因此,上述假设似乎不成立。