Kruse W
Klin Monbl Augenheilkd. 1983 Jun;182(6):582-4. doi: 10.1055/s-2008-1054859.
The beta-blocker Metipranolol is discussed with reference to a pilot study and a double-blind study. It was found to be remarkably effective in lowering intraocular pressure. No statistically significant difference was found between Metipranolol and Timolol with regard to their effect on intraocular pressure and blood circulation. Nor were any significant side effects observed.