通过抗体依赖性巨噬细胞感染性增强进行登革病毒分离
Dengue virus isolation by antibody-dependent enhancement of infectivity in macrophages.
作者信息
Cardosa M J
出版信息
Lancet. 1987 Jan 24;1(8526):193-4. doi: 10.1016/s0140-6736(87)90005-5.
PMID:2880019
Abstract
Acute-phase serum samples collected during an outbreak of dengue fever and dengue haemorrhagic fever in Penang, Malaysia, were tested by a method involving antibody-dependent enhancement of infectivity in the mouse macrophage-like cell line, P388D1. 58 of 71 (81.7%) serologically positive cases yielded virus.
摘要
在马来西亚槟城登革热和登革出血热疫情期间采集的急性期血清样本，采用一种在小鼠巨噬细胞样细胞系P388D1中涉及抗体依赖性感染增强的方法进行检测。71例血清学阳性病例中有58例（81.7%）检测出病毒。
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