Lee Jun Hui, Shi Yuhua, Amoozgar Behzad, Aderman Christopher, De Alba Campomanes Alejandra, Lin Shan, Han Ying
*Department of Ophthalmology, University of California, San Francisco School of Medicine, San Francisco, CA †Department of Ophthalmology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
J Glaucoma. 2017 Oct;26(10):936-939. doi: 10.1097/IJG.0000000000000757.
To study and compare the outcome of micropulse transscelral cyclophotocoagulation in pediatric glaucoma patients to that in adult glaucoma patients.
Consecutive pediatric and adult patients who received micropulse transscelral cyclophotocoagulation between July 2015 and December 2016 at University of California, San Francisco were retrospectively analyzed. All cases had at least 12 months of follow-up.
Nine eyes from 9 pediatric patients and 27 eyes from 25 adult patients were included. The sample size in pediatric group is small because MP-TCP was not offered to pediatric patients after unsatisfactory results in initial cases. Preoperatively, the mean intraocular pressure (IOP) was 28.41±8.32 mm Hg in adult patients and 34.28±9.92 mm Hg in pediatric patients. Postoperatively, the mean IOP in adult patients significantly decreased at all follow-up points (P<0.001). In pediatric patients, the mean IOP decreased to 20.44±13.41 mm Hg at 1 month (P=0.021), 23.56±10.10 mm Hg at 3 months (P=0.093), 23.00±8.31 mm Hg (P=0.018) at 6 months, and 27.20±15.68 mm Hg (P=0.15) at 12 months. No significant complications were noted in either group. The success rate in adults was 72.22% versus 22.22% in pediatric patients at 12 months (P=0.02). Seven of 9 pediatric patients required reoperation during the 12 months of follow-up.
Micropulse transscelral cyclophotocoagulation is a safe procedure for pediatric as well as adult glaucoma patients. Its effect seems to be short lived in pediatric patients and the rate of reoperation was high.
研究并比较小儿青光眼患者与成人青光眼患者接受微脉冲经巩膜睫状体光凝术的治疗结果。
对2015年7月至2016年12月期间在加利福尼亚大学旧金山分校接受微脉冲经巩膜睫状体光凝术的连续小儿和成人患者进行回顾性分析。所有病例均至少随访12个月。
纳入9例小儿患者的9只眼和25例成人患者的27只眼。小儿组样本量较小，因为在最初病例结果不理想后未向小儿患者提供微脉冲经巩膜睫状体光凝术。术前，成人患者平均眼压（IOP）为28.41±8.32 mmHg，小儿患者为34.28±9.92 mmHg。术后，成人患者在所有随访点的平均眼压均显著降低（P<0.001）。小儿患者中，1个月时平均眼压降至20.44±13.41 mmHg（P=0.021），3个月时为23.56±10.10 mmHg（P=0.093），6个月时为23.00±8.31 mmHg（P=0.018），12个月时为27.20±15.68 mmHg（P=0.15）。两组均未发现明显并发症。12个月时成人患者成功率为72.22%，小儿患者为22.22%（P=0.02）。9例小儿患者中有7例在12个月的随访期间需要再次手术。
微脉冲经巩膜睫状体光凝术对小儿和成人青光眼患者都是一种安全的手术。其在小儿患者中的效果似乎是短期的，再次手术率较高。
