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心脏手术后的胃肠道并发症:一项基于全国人口的发病率和死亡率预测因素分析。

Gastrointestinal Complications After Cardiac Surgery: A Nationwide Population-Based Analysis of Morbidity and Mortality Predictors.

作者信息

Chaudhry Rabail, Zaki John, Wegner Robert, Pednekar Greesha, Tse Alex, Sheinbaum Roy, Williams George W

机构信息

Department of Anesthesiology, University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School, Houston, TX.

Department of Anesthesiology, University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School, Houston, TX; Department of Neurosurgery, University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School, Houston, TX.

出版信息

J Cardiothorac Vasc Anesth. 2017 Aug;31(4):1268-1274. doi: 10.1053/j.jvca.2017.04.013. Epub 2017 Apr 13.

Abstract

OBJECTIVE

The authors aimed to evaluate the incidence, risk factors, and outcomes of gastrointestinal (GI) complications in cardiac and aortic surgery using recent versions of the National (Nationwide) Inpatient Sample (NIS) to provide clinicians with a better understanding of these uncommon but potentially serious complications.

DESIGN

Population-based study.

SETTING

NIS database 2010-2012.

PARTICIPANTS

Patients undergoing cardiac and aortic aneurysm repair surgeries.

INTERVENTIONS

Not applicable.

MEASUREMENTS AND MAIN RESULTS

The most common GI complication was postoperative ileus, which also had the lowest mortality, followed by GI hemorrhage. Mesenteric ischemia demonstrated the highest mortality, followed by intestinal perforation. Mortality was highest in those with infective endocarditis (16.02%), followed by myocardial infarction (12.48%). GI complications were highest in patients undergoing repair of abdominal aortic aneurysm, followed by off-pump coronary artery bypass grafting.

CONCLUSION

In conclusion, this study demonstrated that GI complications after cardiac surgery occurred at a rate of 4.17%, which is similar to that reported in the NIS database from 1998 to 2002 in coronary artery bypass grafting patients, but higher than that previously described in single-center studies. GI complications after cardiac surgery increased inpatient mortality 3-fold and more than doubled length of stay. Improved recognition and understanding of the predisposing risk factors and complications elucidated in this study could serve to increase the necessity for timely diagnosis and treatment of patients at high risk for GI complications after cardiac surgery.

摘要

目的

作者旨在利用最新版的全国住院患者样本(NIS)评估心脏和主动脉手术中胃肠道(GI)并发症的发生率、危险因素及预后,以便临床医生更好地了解这些虽不常见但可能严重的并发症。

设计

基于人群的研究。

设置

2010 - 2012年NIS数据库。

参与者

接受心脏和主动脉瘤修复手术的患者。

干预措施

不适用。

测量指标及主要结果

最常见的胃肠道并发症是术后肠梗阻,其死亡率也最低,其次是胃肠道出血。肠系膜缺血的死亡率最高,其次是肠穿孔。感染性心内膜炎患者的死亡率最高(16.02%),其次是心肌梗死患者(12.48%)。腹主动脉瘤修复患者的胃肠道并发症发生率最高,其次是不停跳冠状动脉搭桥术患者。

结论

总之,本研究表明心脏手术后胃肠道并发症的发生率为4.17%,这与1998年至2002年NIS数据库中冠状动脉搭桥术患者的报告发生率相似,但高于先前单中心研究中所描述的发生率。心脏手术后的胃肠道并发症使住院死亡率增加了3倍,住院时间延长了一倍多。更好地认识和理解本研究中阐明的易感危险因素及并发症,可能有助于提高对心脏手术后胃肠道并发症高危患者进行及时诊断和治疗的必要性。

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