Centre for Health Research and Development, Society for Applied Studies, New Delhi, India.
Department of Research, Innlandet Hospital Trust, Bergen, Norway.
BMJ Open. 2017 Aug 11;7(8):e014179. doi: 10.1136/bmjopen-2016-014179.
To examine gender differences in infant survival on the first day of life, in the first week of life, and in the neonatal and post-neonatal periods by socio-demographic and economic variables.
Secondary data analysis was performed on data from a cluster randomised trial on the effect of implementation of the Integrated Management of Neonatal and Childhood Illness programme, India.
The study setting was Palwal and Faridabad, districts of Haryana, a state in North India.
Multiple logistic regression models taking the cluster design into account were used to estimate gender differences in mortality in different periods of infancy.
A total of 60 480 infants were included in these analyses. Of 4060 infant deaths, 2054 were female (7.2% of all females born) and 2006 were male (6.3% of all males born). The death rate was significantly higher in females in the post-neonatal period but not during the neonatal period. The odds of death at 29-180 days and at 181-365 days were 1.4 (95% CI 1.3 to 1.6) and 1.7 (95% CI: 1.4 to 2.0) higher in females compared with males, respectively. This increase was seen across all socio-demographic and economic strata.
Gender differences during the post-neonatal period are a major threat to the survival and health of female infants in India. Programmes need to identify measures that can specifically reduce female mortality.
Clinical trials NCT00474981.
通过社会人口经济学变量,研究生命第一天、第一周以及新生儿和婴儿后期的婴儿生存的性别差异。
对印度实施新生儿和儿童疾病综合管理方案的效果的一项集群随机试验的数据进行二次数据分析。
研究地点位于印度北部哈里亚纳邦的帕尔瓦尔和法里达巴德区。
采用考虑到集群设计的多项逻辑回归模型,估计不同婴儿期的死亡率的性别差异。
共有 60480 名婴儿纳入了这些分析。在 4060 例婴儿死亡中,女性 2054 例(所有女性出生的 7.2%),男性 2006 例(所有男性出生的 6.3%)。女性在后新生儿期的死亡率显著高于男性,但在新生儿期则不然。29-180 天和 181-365 天的死亡风险分别比男性高 1.4 倍(95%CI:1.3 至 1.6)和 1.7 倍(95%CI:1.4 至 2.0)。这种增加在所有社会人口经济学阶层中都存在。
后新生儿期的性别差异是印度女婴生存和健康的主要威胁。方案需要确定可以专门降低女性死亡率的措施。
临床试验 NCT00474981。