Schulz-Schaeffer W J
Institut für Neuropathologie, Universitätsklinikum des Saarlandes, Kirrberger Strasse 100, Gebäude 90.3, 66421, Homburg/Saar, Deutschland.
Radiologe. 2017 Sep;57(9):701-706. doi: 10.1007/s00117-017-0290-3.
The World Health Organization (WHO) provides uniform definitions and a uniform nomenclature for tumors of various organs.
What changes resulted from the 2016 WHO classification of tumors of the central nervous system?
Changes in the definition and classification of brain tumors of the revised WHO classification are presented. Most changes evolve from the results of molecular pathology that were generated during the last decade.
For the first time the WHO classification of brain tumors is not based exclusively on histology. Molecular parameters add to the definition of a number of tumor entities. Especially the chapters of gliomas, medulloblastomas and other embryonal tumors have been restructured.
Advances in molecular pathology require a modular diagnostics scheme that integrates histological and molecular parameters into a final diagnosis. This approach will result in more precise tumor groups with respect to prognosis and therapy.
世界卫生组织（WHO）为各种器官的肿瘤提供统一的定义和命名法。
2016年WHO中枢神经系统肿瘤分类带来了哪些变化？
介绍了WHO修订分类中脑肿瘤定义和分类的变化。大多数变化源自过去十年分子病理学的研究结果。
WHO脑肿瘤分类首次并非仅基于组织学。分子参数补充了许多肿瘤实体的定义。尤其是胶质瘤、髓母细胞瘤和其他胚胎性肿瘤章节已重新构建。
分子病理学的进展需要一种模块化诊断方案，将组织学和分子参数整合到最终诊断中。这种方法将在预后和治疗方面产生更精确的肿瘤分组。
