• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

The effect of CYP2C19 genetic polymorphism and non-genetic factors on clopidogrel platelets inhibition in East Asian coronary artery disease patients.

作者信息

Amin Arwa M, Sheau Chin Lim, Mohamed Noor Dzul Azri, Mostafa Hamza, Abdul Kader Muhamad Ali S K, Kah Hay Yuen, Ibrahim Baharudin

机构信息

School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.

School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.

出版信息

Thromb Res. 2017 Oct;158:22-24. doi: 10.1016/j.thromres.2017.07.032. Epub 2017 Aug 1.

DOI:10.1016/j.thromres.2017.07.032
PMID:28802144
Abstract
摘要

相似文献

1
The effect of CYP2C19 genetic polymorphism and non-genetic factors on clopidogrel platelets inhibition in East Asian coronary artery disease patients.CYP2C19基因多态性及非遗传因素对东亚冠心病患者氯吡格雷血小板抑制作用的影响
Thromb Res. 2017 Oct;158:22-24. doi: 10.1016/j.thromres.2017.07.032. Epub 2017 Aug 1.
2
Impact of CYP3A5 polymorphism on platelet reactivity at percutaneous coronary intervention and after 9 months of aspirin and clopidogrel therapy in Japanese patients with coronary artery disease.CYP3A5基因多态性对日本冠心病患者经皮冠状动脉介入治疗时及阿司匹林和氯吡格雷治疗9个月后的血小板反应性的影响。
Eur J Clin Pharmacol. 2014 Jun;70(6):667-73. doi: 10.1007/s00228-014-1672-3. Epub 2014 Apr 26.
3
Decreased platelet responsiveness to clopidogrel correlates with CYP2C19 and PON1 polymorphisms in atherosclerotic patients.动脉粥样硬化患者中,血小板对氯吡格雷的反应性降低与CYP2C19和PON1基因多态性相关。
Braz J Med Biol Res. 2017 Jan 9;50(1):e5660. doi: 10.1590/1414-431X20165660.
4
Effects of cytochrome P450 2C19 and paraoxonase 1 polymorphisms on antiplatelet response to clopidogrel therapy in patients with coronary artery disease.细胞色素P450 2C19和对氧磷酶1基因多态性对冠心病患者氯吡格雷治疗抗血小板反应的影响。
PLoS One. 2014 Oct 16;9(10):e110188. doi: 10.1371/journal.pone.0110188. eCollection 2014.
5
CYP2C19*2 and Other Allelic Variants Affecting Platelet Response to Clopidogrel Tested by Thrombelastography in Patients with Acute Coronary Syndrome.通过血栓弹力图检测急性冠状动脉综合征患者中影响血小板对氯吡格雷反应的CYP2C19*2及其他等位基因变体
Chin Med J (Engl). 2015 Aug 20;128(16):2183-8. doi: 10.4103/0366-6999.162515.
6
Genetic and non-genetic factors responsible for antiplatelet effects of clopidogrel in Japanese patients undergoing coronary stent implantation: an algorithm to predict on-clopidogrel platelet reactivity.导致日本经皮冠状动脉介入治疗(PCI)术后患者氯吡格雷抗血小板作用的遗传和非遗传因素:预测氯吡格雷抵抗血小板反应的算法。
Thromb Res. 2014 Oct;134(4):877-83. doi: 10.1016/j.thromres.2014.07.018. Epub 2014 Aug 14.
7
Comparison of the antiplatelet effect of clopidogrel hydrogenosulfate and clopidogrel besylate in patients with stable coronary artery disease.硫酸氢氯吡格雷与氯吡格雷硫酸氢盐对稳定型冠状动脉疾病患者抗血小板作用的比较。
J Thromb Thrombolysis. 2015 Oct;40(3):288-93. doi: 10.1007/s11239-015-1173-y.
8
Genetic determinants of high on-treatment platelet reactivity in clopidogrel treated Chinese patients.氯吡格雷治疗的中国患者中治疗时血小板高反应性的遗传决定因素。
Thromb Res. 2013 Jul;132(1):81-7. doi: 10.1016/j.thromres.2013.05.006. Epub 2013 May 29.
9
Clopidogrel response variability: impact of genetic polymorphism and platelet biomarkers for predicting adverse outcomes poststenting.氯吡格雷反应变异性:基因多态性和血小板生物标志物对预测支架置入术后不良结局的影响
Am J Ther. 2015 May-Jun;22(3):222-30. doi: 10.1097/MJT.0000000000000125.
10
The cytochrome 2C19*2 and *3 alleles attenuate response to clopidogrel similarly in East Asian patients undergoing elective percutaneous coronary intervention.细胞色素 2C19*2 和 *3 等位基因在接受择期经皮冠状动脉介入治疗的东亚患者中同样减弱氯吡格雷的反应。
Thromb Res. 2011 Jan;127(1):23-8. doi: 10.1016/j.thromres.2010.10.021.

引用本文的文献

1
Prevalence of clopidogrel resistance in patients with atrial fibrillation undergoing percutaneous coronary intervention.接受经皮冠状动脉介入治疗的心房颤动患者中氯吡格雷抵抗的患病率。
Postepy Kardiol Interwencyjnej. 2025 Jun 5;21(2):259-261. doi: 10.5114/aic.2025.151854. eCollection 2025 Jun.
2
The Frequency of Gene Polymorphisms in Burkina Faso Patients Treated with Clopidogrel.布基纳法索接受氯吡格雷治疗患者的基因多态性频率
Appl Clin Genet. 2025 May 1;18:55-61. doi: 10.2147/TACG.S509095. eCollection 2025.
3
METTL3-mediated methylation of CYP2C19 mRNA may aggravate clopidogrel resistance in ischemic stroke patients.
METTL3介导的CYP2C19 mRNA甲基化可能会加重缺血性中风患者对氯吡格雷的抵抗。
Open Med (Wars). 2024 Feb 7;19(1):20240899. doi: 10.1515/med-2024-0899. eCollection 2024.
4
The Impact of CYP2C19 Genotype on the Platelet Reactivity Index (PRI) among Chronic Coronary Syndromes (CCS) Patients Undergoing Percutaneous Coronary Intervention (PCI): Affectability of Rapid Genetic Testing.CYP2C19基因分型对接受经皮冠状动脉介入治疗(PCI)的慢性冠状动脉综合征(CCS)患者血小板反应指数(PRI)的影响:快速基因检测的敏感性
Cardiovasc Drugs Ther. 2025 Apr;39(2):347-356. doi: 10.1007/s10557-024-07544-6. Epub 2024 Jan 15.
5
The role of clopidogrel resistance-related genetic and epigenetic factors in major adverse cardiovascular events among patients with acute coronary syndrome after percutaneous coronary intervention.氯吡格雷抵抗相关遗传和表观遗传因素在经皮冠状动脉介入治疗后急性冠状动脉综合征患者主要不良心血管事件中的作用
Front Cardiovasc Med. 2023 Feb 8;9:1027892. doi: 10.3389/fcvm.2022.1027892. eCollection 2022.
6
The Role of Genetic Polymorphism and Other Factors on Clopidogrel Resistance (CR) in an Asian Population with Coronary Heart Disease (CHD).基因多态性及其他因素对亚洲冠心病(CHD)人群氯吡格雷抵抗(CR)的作用
Molecules. 2021 Apr 1;26(7):1987. doi: 10.3390/molecules26071987.
7
*2 Polymorphism Related to Clopidogrel Resistance in Patients With Coronary Heart Disease, Especially in the Asian Population: A Systematic Review and Meta-Analysis.2 冠心病患者尤其是亚洲人群中与氯吡格雷抵抗相关的多态性:一项系统评价和荟萃分析。
Front Genet. 2020 Dec 22;11:576046. doi: 10.3389/fgene.2020.576046. eCollection 2020.
8
Comparison between ticagrelor versus clopidogrel in long term outcomes of Taiwanese diabetic subjects with acute coronary syndrome undergoing successful revascularization: From TSOC ACS-DM registry.替格瑞洛与氯吡格雷对台湾急性冠脉综合征合并糖尿病且成功接受血运重建患者长期预后的比较:来自台湾急性冠脉综合征合并糖尿病注册研究(TSOC ACS-DM registry)
Medicine (Baltimore). 2020 May;99(19):e19969. doi: 10.1097/MD.0000000000019969.
9
Platelet inhibitory activity, tolerability, and safety of vicagrel, a novel thienopyridine P2Y12 inhibitor.新型噻吩并吡啶P2Y12抑制剂维卡格雷的血小板抑制活性、耐受性及安全性
Medicine (Baltimore). 2020 Jan;99(4):e18683. doi: 10.1097/MD.0000000000018683.
10
Effects of different CYP2C19 genotypes on prognosis of patients complicated with atrial fibrillation taking clopidogrel after PCI.不同CYP2C19基因型对PCI术后服用氯吡格雷的房颤合并患者预后的影响。
Exp Ther Med. 2018 Oct;16(4):3492-3496. doi: 10.3892/etm.2018.6650. Epub 2018 Aug 22.