Ocak Emre, Kocaoz Deniz, Acar Baran
Department of Otorhinolaryngology, Kecioren Research and Training Hospital, Ankara, Turkey.
Int J Pediatr Otorhinolaryngol. 2017 Sep;100:194-197. doi: 10.1016/j.ijporl.2017.07.010. Epub 2017 Jul 12.
To evaluate the factors which may be related to nonadherence to intranasal corticosteroids (ICS) in the treatment of allergic rhinitis (AR) in children.
A prospective study was conducted on children with AR diagnosis in a tertiary referral hospital. All participants were provided with mometasone furoate nasal sprays for 30 days after the diagnosis. Caregivers were called back when the therapy was over and completed a questionnaire about the factors that may influence the adherence to the treatment. Afterwards each caregiver completed the Turkish language validated Morisky Medical Adherence Scale (MMAS-8) form. Each factor was evaluated according to MMAS-8 score and all variables were analyzed statistically.
A total number of 76 children with a mean age of 7.82 years were included in the study. The mean overall MMAS-8 score was 2.80. There was only one factor significantly related to low adherence; the number of dependent children to the caregiver (p = 0.011). Besides this 71.51% of the answers to MMAS-8 scale were compatible with good adherence.
The clinician must consider the factors which may lead to non-adherence while setting up a treatment plan. The demographic and sociocultural factors must be taken into consideration and treatment schedule should be made in respect of daily activities of the children. Moreover the father can be involved in the therapy plan and back up the mother as they are usually the responsible parent for children's medical therapy.
评估儿童过敏性鼻炎（AR）治疗中可能与不坚持使用鼻用糖皮质激素（ICS）相关的因素。
在一家三级转诊医院对诊断为AR的儿童进行了一项前瞻性研究。所有参与者在诊断后均接受糠酸莫米松鼻喷雾剂治疗30天。治疗结束后回访照顾者，让其完成一份关于可能影响治疗依从性因素的问卷。之后，每位照顾者完成经土耳其语验证的Morisky药物依从性量表（MMAS-8）表格。根据MMAS-8评分对每个因素进行评估，并对所有变量进行统计学分析。
共有76名平均年龄为7.82岁的儿童纳入研究。MMAS-8的总体平均评分为2.80。只有一个因素与低依从性显著相关；依赖照顾者的儿童数量（p = 0.011）。除此之外，MMAS-8量表71.51%的答案与良好依从性相符。
临床医生在制定治疗方案时必须考虑可能导致不依从的因素。必须考虑人口统计学和社会文化因素，并应根据儿童的日常活动制定治疗计划。此外，父亲可以参与治疗计划，并在母亲通常是儿童医疗治疗的主要负责人时给予支持。
