Department of Cardio-Thoracic and Respiratory Science, University of Campania "Luigi Vanvitelli", Naples, Italy; IX Division of General Surgery, Vascular Surgery, and Applied Biotechnology, Naples University Polyclinic, Naples, Italy.
Department of Cardio-Thoracic and Respiratory Science, University of Campania "Luigi Vanvitelli", Naples, Italy.
Surg Obes Relat Dis. 2017 Oct;13(10):1692-1699. doi: 10.1016/j.soard.2017.06.007. Epub 2017 Jul 1.
There is evidence that body composition and resting metabolic rate (RMR) in weight-stable patients after Roux-en-Y gastric bypass and duodenal switch is similar to that of nonoperated individuals within the same body mass index (BMI) interval. Currently, data concerning fat mass (FM), fat-free mass (FFM), and RMR on weight-stable patients after sleeve gastrectomy (SG) are lacking.
To assess FM, FFM, and RMR, in a selected and homogenous population of weight-stable SG patients (WSSG) and compare them with those obtained from healthy normal weight-stable nonoperated (WSNO) volunteers controls of similar sex, age, and BMI.
University hospital, Italy.
We assessed total weight, FM, and FFM by bioelectrical impedance assay, and RMR by indirect calorimetry, in 70 WSSG patients (47 females, 23 males) at a mean follow-up of 3.2 ± 2.1 years after SG and compared them with 70 healthy WSNO volunteers, as controls (47 females, 23 males).
There was no significant difference between WSSG and WSNO groups concerning total weight (males, 72 ± 2.66 versus 72.8 ± 1.99 kg, P = .0254; females 65.1 ± 2.53 versus 63.7 ± 2.87 kg, P = .0139), FM (males, 17.7 ± 1.53 versus 16.7 ± 1.57 kg, P = .0341; females 19.6 ± 0.50 versus 18.5 ± 2.85 kg, P = .0104), FFM (males, 54.3 ± 3.07 versus 56.1 ± 3.30 kg; P = .049; females 45.5 ± 2.29 versus 45.1 ± 1.13 kg, P = .287), and RMR (males, 1541 ± 121.3 versus 1463 ± 74.4 kcal/d; P = .0118; females 1214 ± 54.9 versus 1250 ± 90.1 kcal/d, P = .0215).
At a mean follow-up of 3.2 ± 2.1 years after SG, WSSG patients of both sexes have a FM, FFM, and RMR comparable to that of healthy WSNO individuals within the same age and BMI interval. These findings further support bariatric surgery-induced weight loss as a physiologic process and indicate that young patients, in the setting of an adequate preoperative and postoperative specific diet and moderate physical activity, do not suffer from excessive FFM depletion after SG in the mid-term.
有证据表明，在 Roux-en-Y 胃旁路和十二指肠转位手术后体重稳定的患者中，身体成分和静息代谢率（RMR）与相同 BMI 区间内未接受手术的个体相似。目前，关于袖状胃切除术（SG）后体重稳定患者的脂肪量（FM）、去脂体重（FFM）和 RMR 的数据尚缺乏。
评估选择和同质的 SG 后体重稳定患者（WSSG）的 FM、FFM 和 RMR，并将其与健康、体重稳定的未接受手术（WSNO）志愿者对照者的结果进行比较，这些对照者具有相似的性别、年龄和 BMI。
意大利的一家大学医院。
我们通过生物电阻抗分析法评估了 70 例 WSSG 患者（47 名女性，23 名男性）的总体重、FM 和 FFM，并通过间接热量法评估了 RMR，这些患者在 SG 后平均随访 3.2 ± 2.1 年，并与 70 名健康的 WSNO 志愿者作为对照进行比较（47 名女性，23 名男性）。
WSSG 组和 WSNO 组在总体重方面没有显著差异（男性：72 ± 2.66 与 72.8 ± 1.99 kg，P =.0254；女性：65.1 ± 2.53 与 63.7 ± 2.87 kg，P =.0139）、FM（男性：17.7 ± 1.53 与 16.7 ± 1.57 kg，P =.0341；女性：19.6 ± 0.50 与 18.5 ± 2.85 kg，P =.0104）、FFM（男性：54.3 ± 3.07 与 56.1 ± 3.30 kg；P =.049；女性：45.5 ± 2.29 与 45.1 ± 1.13 kg，P =.287）和 RMR（男性：1541 ± 121.3 与 1463 ± 74.4 kcal/d；P =.0118；女性：1214 ± 54.9 与 1250 ± 90.1 kcal/d，P =.0215）。
在 SG 后平均 3.2 ± 2.1 年的随访中，无论男女，WSSG 患者的 FM、FFM 和 RMR 均与相同年龄和 BMI 区间内健康的 WSNO 个体相当。这些发现进一步支持了减重手术诱导的体重减轻是一种生理性过程，并表明在适当的术前和术后特定饮食以及适度的体力活动的情况下，年轻患者在中期不会因 SG 而遭受过多的 FFM 耗竭。
