Skogar Martin, Holmbäck Ulf, Hedberg Jakob, Risérus Ulf, Sundbom Magnus
Department of Surgical Sciences, Uppsala University, SE-751 85, Uppsala, Sweden.
Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, SE-751 85, Uppsala, Sweden.
Obes Surg. 2017 Jul;27(7):1735-1740. doi: 10.1007/s11695-016-2476-6.
Concerns for the possibility of an excessive loss of fat-free mass (FFM) and resting metabolic rate (RMR) after bariatric surgery, such as Roux-en-Y gastric bypass (RYGB) and duodenal switch (BPD/DS), have been raised.
This study aims to examine body composition and RMR in patients after RYGB and BPD/DS and in non-operated controls.
Body composition and RMR were studied with Bod Pod and indirect calorimetry in weight-stable RYGB (n = 15) and BPD/DS patients (n = 12) and compared with non-operated controls (n = 17). All patients were 30-55 years old and weight stable with BMI 28-35 kg/m.
FFM% was 58% (RYGB), 61% (BPD/DS), and 58% (controls). Body composition did not differ after RYGB and BPD/DS compared to controls, despite 27 and 40% total body weight loss, respectively. No difference in RMR or RMR/FFM was observed (1539, 1617, and 1490 kcal/24 h; and 28.9, 28.4, and 28.8 kcal/24 h/kg).
Weight-stable patients with BMI 28-35 kg/m after RYGB and BPD/DS have a body composition and RMR similar to that of non-operated individuals within the same BMI interval.
人们对减重手术后无脂肪量（FFM）和静息代谢率（RMR）可能过度流失表示担忧，如 Roux-en-Y 胃旁路术（RYGB）和十二指肠转位术（BPD/DS）。
本研究旨在检查接受 RYGB 和 BPD/DS 手术的患者以及未手术对照组的身体成分和 RMR。
采用体脂测量仪和间接测热法对体重稳定的 RYGB 患者（n = 15）和 BPD/DS 患者（n = 12）进行身体成分和 RMR 研究，并与未手术对照组（n = 17）进行比较。所有患者年龄在 30 - 55 岁之间，体重稳定，BMI 为 28 - 35 kg/m²。
FFM%分别为 58%（RYGB）、61%（BPD/DS）和 58%（对照组）。尽管 RYGB 和 BPD/DS 组患者总体重分别下降了 27%和 40%，但与对照组相比，身体成分并无差异。未观察到 RMR 或 RMR/FFM 有差异（分别为 1539、1617 和 1490 kcal/24 小时；以及 28.9、28.4 和 28.8 kcal/24 小时/千克）。
BMI 为 28 - 35 kg/m²且体重稳定的 RYGB 和 BPD/DS 术后患者，其身体成分和 RMR 与相同 BMI 区间内未手术个体相似。
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