Falup-Pecurariu Cristian, Diaconu Ştefania
Faculty of Medicine, Transilvania University, Braşov, România; County Emergency Clinic Hospital, Braşov, România.
County Emergency Clinic Hospital, Braşov, România.
Int Rev Neurobiol. 2017;133:719-742. doi: 10.1016/bs.irn.2017.05.033. Epub 2017 Jul 10.
The spectrum of sleep problems in Parkinson's disease (PD) is broad. These symptoms are recognized as being clinically relevant by the PD patients and may seriously affect their quality of life. Some studies reveal the occurrence of sleep disorders in more than half of the PD patients. The etiology is multifactorial and it mainly involves the degeneration of the sleep-regulating structures. Sleep disorders in PD can be classified into: disturbances of sleep and disturbances of wakefulness. Generic and specific scales were designed to help the screening and evaluation of sleep dysfunction. Further assessment can be done using sleep recording techniques, like actigraphy or polysomnography. All types of sleep disturbances may be encountered in PD: insomnia, excessive daytime sleepiness, rapid eye movement sleep behavior disorders, and restless legs syndrome. This chapter will focus on reviewing the main characteristics, pathophysiology, assessment, and management of the most frequent sleep disturbances encountered in PD.
帕金森病（PD）的睡眠问题范围广泛。这些症状被PD患者认为具有临床相关性，可能严重影响他们的生活质量。一些研究表明，超过一半的PD患者存在睡眠障碍。其病因是多因素的，主要涉及睡眠调节结构的退化。PD中的睡眠障碍可分为：睡眠障碍和觉醒障碍。设计了通用和特定的量表来帮助筛查和评估睡眠功能障碍。可以使用睡眠记录技术，如活动记录仪或多导睡眠图进行进一步评估。PD中可能会出现各种类型的睡眠障碍：失眠、日间过度嗜睡、快速眼动睡眠行为障碍和不宁腿综合征。本章将重点回顾PD中最常见的睡眠障碍的主要特征、病理生理学、评估和管理。
