Newcastle University, UK.
Autism. 2018 Oct;22(7):774-783. doi: 10.1177/1362361317714988. Epub 2017 Aug 12.
Autism spectrum disorder is associated with co-existing conditions that may adversely affect an individual's quality of life. No systematic review of quality of life of adults on the autism spectrum has been conducted. Our objectives were as follows: (1) review the evidence about quality of life for adults on the autism spectrum; (2) critically appraise current practice in assessing quality of life of adults on the autism spectrum. We searched bibliographic databases and other literature to identify studies using a direct measure of quality of life of adults on the autism spectrum. Hand searching of reference lists, citation searching and personal communication with field experts were also undertaken. In total, 827 studies were identified; 14 were included. Only one quality of life measure designed for use with the general autism spectrum population was identified. Quality of life of adults on the autism spectrum is lower than that of typically developing adults, when measured with tools designed for the general population. There are no comprehensive autism spectrum disorder-specific quality of life measurement tools validated for use with representative samples of adults on the autism spectrum. There is a pressing need to develop robust measures of quality of life of autistic adults.
自闭症谱系障碍与共存状况有关，这些共存状况可能会对个人的生活质量产生不利影响。目前尚未对自闭症谱系障碍患者的生活质量进行系统的综述。我们的目的如下：（1）综述自闭症谱系障碍患者生活质量的证据；（2）批判性评估目前评估自闭症谱系障碍患者生活质量的实践情况。我们搜索了文献数据库和其他文献，以确定使用自闭症谱系障碍患者直接生活质量衡量标准的研究。此外，我们还进行了参考文献列表的手工搜索、引文搜索和与领域专家的个人交流。总共确定了 827 项研究，其中 14 项被纳入。仅确定了一种专为一般自闭症谱系人群设计的生活质量衡量标准。当使用专为一般人群设计的工具测量时，自闭症谱系障碍患者的生活质量低于典型发育成人。目前还没有针对自闭症谱系障碍患者的全面的生活质量测量工具，也没有经过代表性样本验证的。迫切需要开发出针对自闭症成年患者的可靠生活质量衡量标准。
