School of Psychology, University of Nottingham, UK.
Institute of Neuroscience, Newcastle University, UK.
Autism Res. 2018 May;11(5):738-754. doi: 10.1002/aur.1922. Epub 2018 Jan 23.
Depression is the most commonly experienced mental health condition in adults with autism spectrum conditions (ASC). However, it is unclear what tools are currently being used to assess depression in ASC, or whether tools need to be adapted for this group. This systematic review therefore aimed to identify tools used to assess depression in adults with and without ASC, and then evaluate these tools for their appropriateness and measurement properties. Medline, PsychINFO and Web of Knowledge were searched for studies of depression in: (a) adults with ASC, without co-morbid intellectual disability; and (b) adults from the general population without co-morbid conditions. Articles examining the measurement properties of these tools were then searched for using a methodological filter in PubMed, and the quality of the evidence was evaluated using the COSMIN checklist. Twelve articles were identified which utilized three tools to assess depression in adults with ASC, but only one article which assessed the measurement properties of one of these tools was identified and thus evaluated. Sixty-four articles were identified which utilized five tools to assess depression in general population adults, and fourteen articles had assessed the measurement properties of these tools. Overall, two tools were found to be robust in their measurement properties in the general population-the Beck Depression Inventory (BDI-II), and the patient health questionnaire (PHQ-9). Crucially only one study was identified from the COSMIN search, which showed weak evidence in support of the measurement properties of the BDI-II in an ASC sample. Implications for effective measurement of depression in ASC are discussed. Autism Res 2018, 11: 738-754. © 2018 The Authors Autism Research published by International Society for Autism Research and Wiley Periodicals, Inc.
Depression is the most common mental health problem experienced by adults with autism. However, the current study found very limited evidence regarding how useful tools developed for the general population are for adults with autism. We therefore suggest how these tools could be adapted to more effectively assess depression in adults with autism, and improve these individuals access to mental health assessment and support.
在自闭症谱系障碍（ASC）的成年人中，抑郁症是最常见的心理健康问题。然而，目前尚不清楚目前用于评估 ASC 中抑郁症的工具是什么，或者这些工具是否需要针对该人群进行调整。因此，本系统评价旨在确定用于评估 ASC 成人和非 ASC 成人抑郁症的工具，然后评估这些工具的适宜性和测量特性。在 Medline、PsychINFO 和 Web of Knowledge 中搜索了以下两个方面的研究：（a）无共患智力障碍的 ASC 成人；和（b）无共患疾病的普通人群成人。然后，使用 PubMed 中的方法学过滤器搜索了这些工具的测量特性的文章，并使用 COSMIN 清单评估了证据的质量。确定了 12 篇文章，这些文章使用三种工具来评估 ASC 成人的抑郁症，但仅确定了一篇评估其中一种工具的测量特性的文章，并对其进行了评估。确定了 64 篇文章，这些文章使用五种工具来评估普通人群成人的抑郁症，并且有 14 篇文章评估了这些工具的测量特性。总体而言，在普通人群中，有两种工具被发现具有可靠的测量特性-贝克抑郁自评量表（BDI-II）和患者健康问卷（PHQ-9）。至关重要的是，从 COSMIN 搜索中仅确定了一项研究，该研究表明在 ASC 样本中，BDI-II 的测量特性的证据较弱。讨论了在 ASC 中有效测量抑郁症的影响。自闭症研究 2018，11：738-754。©2018 自闭症研究国际协会和 Wiley 期刊出版公司。
抑郁症是自闭症成人最常见的心理健康问题。然而，目前的研究发现，关于用于普通人群的工具对自闭症成人的有用性的证据非常有限。因此，我们建议如何调整这些工具，以更有效地评估自闭症成人的抑郁症，并改善这些人的心理健康评估和支持的途径。
