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帕金森病中的性功能障碍:一种在备受讨论的疾病中被低估的问题。

Sexual Dysfunctions in Parkinson's Disease: An Underrated Problem in a Much Discussed Disorder.

作者信息

Bhattacharyya Kalyan B, Rosa-Grilo Miguel

机构信息

RG Kar Medical College & Hospital, Kolkata, India.

National Parkinson Foundation (NPF) International Center of Excellence at King's College Hospital, London, United Kingdom; The Maurice Wohl Clinical Neuroscience Institute, King's College London, London, United Kingdom; National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre, Institute of Psychology, Psychiatry and Neurosciences, King's College London, London, United Kingdom.

出版信息

Int Rev Neurobiol. 2017;134:859-876. doi: 10.1016/bs.irn.2017.05.019. Epub 2017 Jun 27.

Abstract

Sexual dysfunctions (SDs) are one of the most neglected nonmotor symptoms in Parkinson's disease (PD). A number of reasons including social and cultural factors might explain, at least partially, why SD is still one of the most underrecognized aspects of the condition after 200 years since the very first description by James Parkinson. SD has not been extensively investigated, however, a number of studies have shown a high prevalence of decreased libido, orgasmic dysfunction in both men and women with PD, and erectile dysfunction in male subjects. Moreover, SD in PD also comprises the increasingly recognized hypersexuality that is often associated with PD treatment. Taken together, SD in PD includes a remarkable range of symptoms and conditions that often require a multidisciplinary approach regarding assessment, investigation, and treatment.

摘要

性功能障碍(SDs)是帕金森病(PD)中最被忽视的非运动症状之一。包括社会和文化因素在内的诸多原因,或许至少能部分解释为何自詹姆斯·帕金森首次描述该病200年后,SD仍是该病症最未得到充分认识的方面之一。SD尚未得到广泛研究,不过,多项研究表明,PD患者中无论男女,性欲减退、性高潮功能障碍以及男性勃起功能障碍的患病率都很高。此外,PD中的SD还包括越来越被认可的与PD治疗相关的性欲亢进。综上所述,PD中的SD包括一系列显著的症状和情况,在评估、调查和治疗方面往往需要多学科方法。

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