Heidary Gena
Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
J Neuroophthalmol. 2017 Sep;37 Suppl 1:S4-S13. doi: 10.1097/WNO.0000000000000549.
The topic of pediatric neurodegenerative disease is broad and ever expanding. Children who suffer from neurodegenerative disease often have concomitant visual dysfunction. Neuro-ophthalmologists may become involved in clinical care to identify corroborating eye findings when a specific condition is suspected, to monitor for disease progression, and in some cases, to assess treatment efficacy. Ophthalmic findings also may be the harbinger of a neurodegenerative process so a keen awareness of the possible manifestations of these conditions is important. The purpose of this review is to highlight common examples of the neuro-ophthalmic manifestations of pediatric neurodegenerative disease using a case-based approach in an effort to provide a framework for approaching these complex patients.
小儿神经退行性疾病这一主题广泛且不断扩展。患有神经退行性疾病的儿童常常伴有视觉功能障碍。当怀疑患有特定疾病时，神经眼科医生可能会参与临床护理，以识别相关的眼部检查结果，监测疾病进展，并且在某些情况下，评估治疗效果。眼科检查结果也可能是神经退行性病变的先兆，因此敏锐地认识这些疾病的可能表现很重要。本综述的目的是采用基于病例的方法，突出小儿神经退行性疾病神经眼科表现的常见实例，以便为诊治这些复杂患者提供一个框架。
