Wu Wen-Jie, Huang Ming-Wei, Gao Yan, Zhang Jian-Guo
Resident, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Associate Professor, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
J Oral Maxillofac Surg. 2018 Mar;76(3):670-675. doi: 10.1016/j.joms.2017.07.151. Epub 2017 Jul 20.
A cystadenoma originating in the salivary gland is a rare neoplasm that can originate from the major or minor salivary glands. Although this tumor has the potential to recur if it is incompletely excised, it has been regarded as a benign tumor because it has not been determined to be associated with local tissue destruction or metastasis. This report serves as an update to the current understanding of cystadenoma. The patient in this case study presented with a recurrent painless mass in her left retromolar and submandibular regions that had persisted for more than 2 years. Histologic analysis showed that this lesion was a recurrent cystadenoma of the minor salivary gland, with cervical lymph nodes testing positive for tumor cells. After more than 3 years of clinical follow-up, no signs of recurrence were observed. A case of cystadenoma with cervical metastasis is presented; further attention should be paid to patients with recurrent cystadenoma that also might contain lymph node metastasis.
起源于唾液腺的囊腺瘤是一种罕见的肿瘤，可起源于大唾液腺或小唾液腺。尽管该肿瘤如果切除不完全有复发的可能，但由于尚未确定其与局部组织破坏或转移有关，因此一直被视为良性肿瘤。本报告旨在更新目前对囊腺瘤的认识。本病例研究中的患者左磨牙后区和下颌下区出现复发性无痛肿块，持续超过2年。组织学分析显示，该病变为小唾液腺复发性囊腺瘤，颈部淋巴结肿瘤细胞检测呈阳性。经过3年多的临床随访，未观察到复发迹象。本文报告一例伴有颈部转移的囊腺瘤病例；对于复发性囊腺瘤且可能伴有淋巴结转移的患者应予以进一步关注。
