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以颈部肿块为首发临床表现的未被怀疑的转移性精原细胞瘤

Cervical mass as the first clinical manifestation of unsuspected metastatic seminoma.

作者信息

Ferri Emanuele, Pedruzzi Barbara, Gasparin Pierpaola, Lunghi Marcello

机构信息

ENT Department, "Madre Teresa di Calcutta" Hospital, Via Albere, 30, Monselice, Padua, Italy.

ENT Department, "Madre Teresa di Calcutta" Hospital, Via Albere, 30, Monselice, Padua, Italy.

出版信息

Auris Nasus Larynx. 2018 Jun;45(3):626-629. doi: 10.1016/j.anl.2017.07.015. Epub 2017 Aug 12.

DOI:10.1016/j.anl.2017.07.015
PMID:28807530
Abstract

The authors reported a case of a 27-year-old man with a nontender left neck mass that had grown quite rapidly within few weeks. FNAB and CT were not consistent to establish the definite diagnosis. After excisional biopsy, the histopathological examination and the immunohistochemical study of the specimen revealed a cervical metastasis of seminoma. The patient was treated with chemotherapy with a complete clinical remission. This uncommon case-report can represent a great diagnostic and therapeutic challenge and should be considered in the differential diagnosis of every cervical masses occurring in young males patients. Diagnostic delays are unfortunately common and may lead to metastatic spread and worse prognosis.

摘要

作者报告了一例27岁男性病例,其左颈部有一无痛性肿块,在几周内迅速增大。细针穿刺抽吸活检(FNAB)和计算机断层扫描(CT)结果不一致,无法明确诊断。切除活检后,对标本进行的组织病理学检查和免疫组化研究显示为精原细胞瘤颈部转移。该患者接受了化疗,临床完全缓解。这个罕见的病例报告可能带来巨大的诊断和治疗挑战,在年轻男性患者出现的每一例颈部肿块的鉴别诊断中都应予以考虑。不幸的是,诊断延迟很常见,可能导致转移扩散和更差的预后。

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Cervical mass as the first clinical manifestation of unsuspected metastatic seminoma.以颈部肿块为首发临床表现的未被怀疑的转移性精原细胞瘤
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