Ng Mitchell, Song Simon, Piuzzi Nicolas S, Ng Kenneth, Gwam Chukwuweike, Mont Michael A, Muschler George F
Cleveland Clinic, Department of Orthopedic Surgery, Cleveland, Ohio, USA.
Duke University, Department of Biomedical Engineering, Durham, North Carolina, USA.
Cytotherapy. 2017 Oct;19(10):1131-1139. doi: 10.1016/j.jcyt.2017.07.006. Epub 2017 Aug 12.
Treatments based on stem cells have long been heralded for their potential to drive the future of regenerative medicine and have inspired increasing medical and business interest. The stem cell therapy market has been expanding since 2012, but earnings and profitability still lag the broader health care sector (compounded annual growth rate in annual financing of 31.5% versus 13.4%, respectively). On the basis of historical financial data, approximately $23 billion has been invested in stem cell companies since 1994, with more than 80% of this raised from 2011 through 2016. This reflects a marked acceleration in capital investment, as companies began late-stage clinical trials, initiate partnerships or are acquired by large pharmaceutical companies. All of these data reflect a field that is emerging from infancy, which will demand more time and capital to mature. This update is relevant to researchers, clinicians and investors who wish to quantify the potential in this field.
基于干细胞的治疗方法长期以来一直因其推动再生医学未来发展的潜力而备受赞誉,并引发了越来越多的医学和商业关注。自2012年以来,干细胞治疗市场一直在扩大,但收益和盈利能力仍落后于更广泛的医疗保健行业(年度融资的复合年增长率分别为31.5%和13.4%)。根据历史财务数据,自1994年以来,已向干细胞公司投资约230亿美元,其中80%以上是在2011年至2016年期间筹集的。这反映出随着公司开始进行后期临床试验、建立合作伙伴关系或被大型制药公司收购,资本投资显著加速。所有这些数据都反映出该领域正从起步阶段兴起,还需要更多时间和资金才能成熟。本更新内容对希望量化该领域潜力的研究人员、临床医生和投资者具有参考价值。