Krull F, Risse A
Fortschr Neurol Psychiatr. 1986 Dec;54(12):398-401. doi: 10.1055/s-2007-1001945.
We report the case of a 22-year-old schizophrenic patient who developed a neuroleptic malignant syndrome under treatment with Benperidol, Levomepromazin and Biperiden. Clinical signs were: fever, rigidity, altered consciousness and rhabdomyolysis of hip-abductors. Intravenous injection of physostigmine led to clearing of consciousness, whereas there seemed to be no impact on fever and rigidity.