通过限制性酶切片段长度多态性鉴定一个新的与HLA - B7相关的21 - 羟化酶缺乏症基因。 - Suppr

Suppr

超能文献

Identification of a new HLA-B7-associated C21-hydroxylase deficiency gene by restriction enzyme length polymorphism.

作者信息

Keller E, Andreas-Zietz A, Knorr D, Scholz S, Albert E D

出版信息

Immunogenetics. 1987;25(2):123-5. doi: 10.1007/BF00364278.

DOI:10.1007/BF00364278

PMID:2880800

Abstract

摘要

相似文献

Identification of a new HLA-B7-associated C21-hydroxylase deficiency gene by restriction enzyme length polymorphism.通过限制性酶切片段长度多态性鉴定一个新的与HLA - B7相关的21 - 羟化酶缺乏症基因。

Immunogenetics. 1987;25(2):123-5. doi: 10.1007/BF00364278.

[Steroid 21-hydroxylase deficiency--congenital adrenal hyperplasia].

Tanpakushitsu Kakusan Koso. 1988 Apr;33(5):903-8.

[Localization of the pathologic gene for 21-hydroxylase enzyme deficiency within the HLA system].[21-羟化酶缺乏症病理基因在HLA系统中的定位]

Lijec Vjesn. 1988 Sep-Oct;110(9-10):306-11.

Classical and late-onset forms of congenital adrenal hyperplasia caused by 21-OH deficiency reveal different alterations in the C4/21-OH gene region.由21-羟化酶缺乏引起的先天性肾上腺皮质增生症的经典型和迟发型在C4/21-羟化酶基因区域表现出不同的改变。

Mol Biol Med. 1986 Oct;3(5):437-48.

Heterogeneity of steroid 21-hydroxylase genes in classical congenital adrenal hyperplasia.

J Immunogenet. 1987 Apr-Jun;14(2-3):89-98. doi: 10.1111/j.1744-313x.1987.tb00367.x.

[Genetics of 21-hydroxylase deficiency].[21-羟化酶缺乏症的遗传学]

Arch Fr Pediatr. 1987 Feb;44(2):75-8.

[Contribution of genetics and molecular biology to the understanding of 21-hydroxylase deficiency].[遗传学和分子生物学对理解21-羟化酶缺乏症的贡献]

Presse Med. 1987 Mar 14;16(9):421-2.

DNA polymorphism unique for a complotype with deletion of HLA-linked C4B and 21-hydroxylase B genes causing congenital adrenal hyperplasia.一种单倍体型特有的DNA多态性，伴有HLA连锁的C4B和21-羟化酶B基因缺失，导致先天性肾上腺皮质增生。

Hum Genet. 1988 Apr;78(4):372-3. doi: 10.1007/BF00291739.

Major-histocompatibility-complex gene markers and restriction-fragment analysis of steroid 21-hydroxylase (CYP21) and complement C4 genes in classical congenital adrenal hyperplasia patients in a single population.单一人群中经典型先天性肾上腺皮质增生症患者的主要组织相容性复合体基因标记以及类固醇21-羟化酶（CYP21）和补体C4基因的限制性片段分析

Am J Hum Genet. 1989 May;44(5):660-70.

[Genetic of the 21 hydroxylase deficiency].[21-羟化酶缺乏症的遗传学]

Ann Endocrinol (Paris). 1982;43(1):3-14.

引用本文的文献

Extensive genomic polymorphism in mouse 21-hydroxylase region.小鼠21-羟化酶区域广泛的基因组多态性。

Immunogenetics. 1988;27(2):133-6. doi: 10.1007/BF00351087.

Am J Hum Genet. 1989 May;44(5):660-70.

本文引用的文献

Cloning and expression of cDNA encoding a bovine adrenal cytochrome P-450 specific for steroid 21-hydroxylation.编码牛肾上腺甾体21-羟化特异性细胞色素P-450的cDNA的克隆与表达。

Proc Natl Acad Sci U S A. 1984 Apr;81(7):1986-90. doi: 10.1073/pnas.81.7.1986.

HLA-linked congenital adrenal hyperplasia results from a defective gene encoding a cytochrome P-450 specific for steroid 21-hydroxylation.与HLA相关的先天性肾上腺皮质增生症是由一个有缺陷的基因引起的，该基因编码一种对类固醇21-羟化作用具有特异性的细胞色素P-450。

Proc Natl Acad Sci U S A. 1984 Dec;81(23):7505-9. doi: 10.1073/pnas.81.23.7505.

MHC "supratype" predicting heterozygous 21-hydroxylase deficiency.

Lancet. 1983 Apr 2;1(8327):764-5. doi: 10.1016/s0140-6736(83)92050-0.

Mapping of steroid 21-hydroxylase genes adjacent to complement component C4 genes in HLA, the major histocompatibility complex in man.人类主要组织相容性复合体HLA中，类固醇21-羟化酶基因与补体成分C4基因的定位。

Proc Natl Acad Sci U S A. 1985 Jan;82(2):521-5. doi: 10.1073/pnas.82.2.521.

Two genes encoding steroid 21-hydroxylase are located near the genes encoding the fourth component of complement in man.编码类固醇21-羟化酶的两个基因位于人类补体第四成分编码基因附近。

Proc Natl Acad Sci U S A. 1985 Feb;82(4):1089-93. doi: 10.1073/pnas.82.4.1089.

Detection of specific sequences among DNA fragments separated by gel electrophoresis.在通过凝胶电泳分离的DNA片段中检测特定序列。

J Mol Biol. 1975 Nov 5;98(3):503-17. doi: 10.1016/s0022-2836(75)80083-0.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验