Nabavizadeh Mohammadreza, Moazzami Fariborz, Bahmani Mohsen, Mirhadi Hossein
Oral and Dental Disease Research Center, Dental School, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Endodontics, Dental school, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran Endod J. 2017 Summer;12(3):329-333. doi: 10.22037/iej.v12i3.15978.
The purpose of this study was to evaluate the effect of calcium hydroxide, double and triple antibiotic paste on the sealing ability of mineral trioxide aggregate (MTA) apical plugs.
A total of 90 extracted teeth with single canals were prepared and randomly divided into four experimental groups (=20). Intra-canal medicaments were applied for 3 weeks. MTA was placed through the access opening and condensed to the apical area and then fluid filtration technique was utilized to evaluate sealing ability after 1, 7, 14 and 30 days.
Triple antibiotic paste significantly reduced the sealing ability of MTA plug compared with double antibiotic paste (=0.024) and normal saline (=0.04) groups on day 1. The sealing ability was not different on days 14 and 30 between experimental groups (>0.05).
All medicaments can be used without any long term effect on microleakage.
本研究的目的是评估氢氧化钙、双联和三联抗生素糊剂对三氧化矿物凝聚体（MTA）根尖封闭剂封闭能力的影响。
总共90颗单根管离体牙被制备并随机分为四个实验组（每组n = 20）。根管内药物应用3周。通过髓腔开口放置MTA并向根尖区加压，然后在1、7、14和30天后利用液体过滤技术评估封闭能力。
在第1天，与双联抗生素糊剂组（P = 0.024）和生理盐水组（P = 0.04）相比，三联抗生素糊剂显著降低了MTA封闭剂的封闭能力。在第14天和第30天，实验组之间的封闭能力没有差异（P>0.05）。
所有药物均可使用，且对微渗漏无长期影响。
