Department of Pharmaceutics and Pharmaceutical Technology, School of Pharmacy, The University of Jordan, Amman 11942, Jordan.
Department of Pharmaceutical Sciences and Pharmaceutics, Faculty of Pharmacy, Applied Science Private University, Amman 11931, Jordan.
Int J Biol Macromol. 2018 Jan;106:360-368. doi: 10.1016/j.ijbiomac.2017.08.024. Epub 2017 Aug 12.
In this study, we evaluate the influence of zein aggregation in aqueous ethanol dispersions on the properties of zein films. The effects of zein concentration, ethanol content and temperature on transmittance of zein dispersions were investigated. Dynamic light scattering was used to measure the degree of zein aggregation in the dispersions. The results indicate that particle size of zein increased with higher zein concentration, lower ethanol level and at lower temperatures. Zein films were prepared by casting from 70% and 90% aqueous ethanol dispersions at different drying temperatures and were evaluated for appearance, thermomechanical and mechanical properties. Higher ethanol levels and higher drying temperatures promoted the formation of more homogenous films. Films made from higher ethanol dispersions had lower glass transition temperatures than those made from lower ethanol dispersions. Moreover, the fragility factor classified the films as strong systems. Mechanical properties of films were measured at different drying temperatures. Stiffer and more resistant films were developed as the drying temperature increased. In conclusion, film properties can be tailored by controlling the composition of the film casting solvent and the drying temperature. Differences in film properties were found to relate to differences in initial degree of aggregation of zein dispersions.
在这项研究中，我们评估了玉米醇溶蛋白在含水乙醇分散体中的聚集对玉米醇溶蛋白膜性能的影响。考察了玉米醇溶蛋白浓度、乙醇含量和温度对玉米醇溶蛋白分散体透光率的影响。动态光散射用于测量分散体中玉米醇溶蛋白聚集的程度。结果表明，随着玉米醇溶蛋白浓度的增加、乙醇水平的降低和温度的降低，玉米醇溶蛋白的粒径增大。通过将 70%和 90%的含水乙醇分散体浇铸在不同干燥温度下制备玉米醇溶蛋白膜，并对其外观、热机械和机械性能进行评估。较高的乙醇水平和较高的干燥温度促进了更均匀的膜的形成。由较高乙醇分散体制备的膜的玻璃化转变温度低于由较低乙醇分散体制备的膜。此外，脆性因子将这些膜分类为强体系。在不同的干燥温度下测量了膜的力学性能。随着干燥温度的升高，开发出了更硬和更耐撕裂的膜。总之，可以通过控制膜浇铸溶剂的组成和干燥温度来定制膜的性能。发现膜性能的差异与玉米醇溶蛋白分散体初始聚集程度的差异有关。
