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以快速生长的阴囊肿胀为表现的婴儿黑素性神经外胚层肿瘤:病例报告及文献综述

Melanotic Neuroectodermal Tumor of Infancy Presenting With Fast-Growing Scrotal Swelling: A Case Report and Literature Review.

作者信息

Fabien-Dupuis Corinthia, Niver Benjamin, Shillingford Nick, Wang Larry, Kokorowski Paul J, Zhou Shengmei

机构信息

1 Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.

2 Department of Pathology, Queen Elizabeth Hospital, Bridgetown, Barbados.

出版信息

Pediatr Dev Pathol. 2017 Sep-Oct;20(5):411-415. doi: 10.1177/1093526616686437. Epub 2017 Jan 25.

Abstract

Testicular melanotic neuroectodermal tumor of infancy (MNTI) is extremely rare, with 2 cases reported in the literature. Its rarity and rapid and infiltrative growth pattern pose a diagnostic challenge. A previously healthy 3-month-old male, presented with a history of worsening left hemiscrotal swelling for 1 week. An outside ultrasound was suggestive of testicular torsion. Left orchiectomy demonstrated a mass occupying almost entire testicle with a variegated cut surface, with areas of pigmentation, necrosis, and hemorrhage. Histological examination confirmed MNTI of the testis and epididymis. MNTI should be included in differential diagnosis in infants presenting with fast-growing scrotal swelling.

摘要

婴儿睾丸黑色素性神经外胚层肿瘤(MNTI)极为罕见,文献中仅报道过2例。其罕见性以及快速浸润性生长模式给诊断带来了挑战。一名此前健康的3个月大男性,有左侧阴囊肿胀加重1周的病史。外院超声提示睾丸扭转。左侧睾丸切除术显示一个肿块几乎占据整个睾丸,切面呈杂色,有色素沉着、坏死和出血区域。组织学检查证实为睾丸及附睾的MNTI。对于出现快速生长的阴囊肿胀的婴儿,鉴别诊断时应考虑MNTI。

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