Rafailov Leon, Turbin Roger E, Langer Paul D
a Institute of Ophthalmology and Visual Science , Rutgers New Jersey Medical School , Newark, New Jersey , USA.
Orbit. 2017 Dec;36(6):397-400. doi: 10.1080/01676830.2017.1337199. Epub 2017 Aug 16.
To describe the novel use of a bilayer dermal substitute to reconstruct exenterated orbits. A retrospective chart review was performed in the practices of two surgeons (RET and PDL) of all patients who had undergone orbital exenteration between April 2014 and June 2016 and whose subsequent reconstruction included lining the socket with Integra bilayer. Patient demographics, pathologic diagnoses, surgical and post-operative complications, graft integrity, and patient acceptance were recorded. The charts of 7 patients (4 men and 3 women, ages 60-87 years) were reviewed. In all cases, the Integra graft had taken well to the socket bed at the time of silicone removal 3-4 weeks after surgery. Epithelialization of the socket occurred rapidly over the Integra graft (within several weeks) without incident in each case and with minimal postoperative management. No intraoperative or postoperative complications were noted. Integra dermal substitute is an ideal graft for the lining of an exenterated orbit. It is readily available in large quantities, handles easily, lines the socket smoothly, epithelializes rapidly, and requires minimal postoperative care. It offers minimal morbidity compared to skin grafting or free flap reconstruction, but greatly speeds epithelialization compared to laissez faire management. Surgeons should consider reconstructing exenterated orbits with the Integra matrix, both for its ease of use and its ability to epithelialize rapidly.
描述一种双层真皮替代物在眼眶内容剜除术后眼眶重建中的新应用。对两位外科医生(RET和PDL)在2014年4月至2016年6月期间所有接受眼眶内容剜除术且后续重建包括使用Integra双层材料衬里眼窝的患者进行回顾性病历审查。记录患者人口统计学资料、病理诊断、手术及术后并发症、移植物完整性和患者接受情况。审查了7例患者(4例男性和3例女性,年龄60 - 87岁)的病历。在所有病例中,术后3 - 4周取出硅胶时,Integra移植物与眼窝床贴合良好。眼窝在Integra移植物上迅速上皮化(数周内),每例均无并发症,术后管理极少。未发现术中或术后并发症。Integra真皮替代物是眼眶内容剜除术后眼窝衬里的理想移植物。它易于大量获取,操作简便,能使眼窝平滑衬里,上皮化迅速,术后护理需求极少。与皮肤移植或游离皮瓣重建相比,它的发病率极低,但与放任管理相比,能极大加快上皮化。外科医生应考虑使用Integra基质重建眼眶内容剜除术后的眼眶,这既因其使用方便,也因其能迅速上皮化。