Ameloot F, Mezzine H, Khairallah G, Hayek G, Zaidi M, Lhuillier L, Talbi M, Sot M, Perone J M
Département d'ophtalmologie, Mercy Hospital, Regional Hospital Center of Metz-Thionville, 1, allée du château, CS 45001, 57085 Metz Cedex 03, France.
Service de chirurgie maxillo-faciale, Mercy Hospital, Regional Hospital Center of Metz-Thionville, 57085 Metz Cedex 3, France.
J Fr Ophtalmol. 2019 Sep;42(7):746-752. doi: 10.1016/j.jfo.2019.03.023. Epub 2019 Jun 14.
The authors report their experience with the use of Integra dermal substitute, in combination with a thin skin graft, following an orbital exenteration. The clinical case described relates to a 42-year-old gentleman with an ulcerative retractile lesion of the right lower eyelid. Histopathological examination diagnosed a moderately differentiated epidermoid carcinoma infiltrating the orbit. Total exenteration was necessary as well as secondary radiation therapy and chemotherapy. Rehabilitation of the exenterated socket was performed by inserting an Integra patch, followed by an additional thin skin graft one month later. The authors review the various available techniques for exenterations, their indications and the various possible secondary rehabilitations. Despite being less utilized, the dermal substitute technique, which is relatively new, seems to offer quicker and easier rehabilitation compared to traditional techniques. A comparative study would be necessary to define superiority among the different techniques of exenteration, with respect to the speed of rehabilitation and resistance to radiation therapy.
作者报告了他们在眼眶内容剜除术后使用Integra真皮替代物联合薄皮片移植的经验。所描述的临床病例是一位42岁男性，右下眼睑有溃疡性退缩性病变。组织病理学检查诊断为中度分化的表皮样癌浸润眼眶。需要进行全眶内容剜除术以及辅助放疗和化疗。通过植入Integra补片对剜除后的眼窝进行修复，一个月后再进行一次薄皮片移植。作者回顾了眼眶内容剜除术的各种可用技术、其适应证以及各种可能的二期修复方法。尽管使用较少，但相对较新的真皮替代物技术与传统技术相比，似乎能提供更快、更简便的修复。有必要进行一项比较研究，以确定不同眼眶内容剜除术技术在修复速度和放疗耐受性方面的优势。
