Cardiovascular Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104; email:
Annu Rev Med. 2018 Jan 29;69:165-176. doi: 10.1146/annurev-med-041316-090545. Epub 2017 Aug 16.
Peripartum cardiomyopathy (PPCM) is the unexplained loss of maternal cardiac systolic function in the period surrounding parturition. PPCM affects women worldwide and is a leading cause of maternal mortality. The cause of PPCM has remained elusive until recently. We review here the epidemiology of PPCM, recent findings that strongly indicate hormonal and genetic contributions to the development of PPCM, and implications for the management of women with PPCM.
围产期心肌病（PPCM）是指在分娩前后期间，产妇心脏收缩功能不明原因丧失。PPCM 影响全球范围内的女性，是产妇死亡的主要原因之一。直到最近，PPCM 的病因仍然难以捉摸。我们在这里回顾了 PPCM 的流行病学，以及最近的发现，这些发现强烈表明激素和遗传因素对 PPCM 的发展有贡献，并对 PPCM 妇女的管理产生影响。
