Walvoort H C, Gruys E, van Dijk J E
Tijdschr Diergeneeskd. 1987 Feb 15;112(4):204-10.
With reference to sixteen cases of polyarteritis nodosa (seven dogs, two cats, two goats, three pigs, two cattle), current views regarding classification, aetiology and pathogenesis of this disease are discussed. Polyartertis nodosa is not a disease entity, but rather a symptom that may be associated with various forms of disease and may vary in pathogenesis. The clinical picture depends upon the localisation of the vasculitis. Toxic agents and various viruses may be directly responsible for the vascular lesions. In addition, genetic, autoimmune and allergic factors may be implicated. The immunological pathogenesis is illustrated with reference to the serum sickness model.
关于16例结节性多动脉炎（7只犬、2只猫、2只山羊、3头猪、2头牛），讨论了目前对该病分类、病因和发病机制的观点。结节性多动脉炎不是一种独立的疾病实体，而是一种可能与多种疾病形式相关且发病机制可能不同的症状。临床表现取决于血管炎的部位。有毒物质和各种病毒可能直接导致血管病变。此外，遗传、自身免疫和过敏因素可能也有牵连。参照血清病模型阐述了免疫发病机制。
