Pumarola M, Brevik L, Badiola J, Vargas A, Domingo M, Ferrer L
Pathology Department, Faculty of Veterinary Medicine, Autonomous University of Barcelona, U.A.B., Bellaterra, Spain.
J Comp Pathol. 1991 Oct;105(3):279-86. doi: 10.1016/s0021-9975(08)80196-x.
Two cases of canine leishmaniasis associated with systemic necrotizing vasculitis are described. The main macroscopic lesions were haemorrhagic in type; histopathological changes confirmed a vascular lesion affecting small arteries of several organs (skin, intestinal tract, kidney, urinary bladder, mesenteric lymph nodes, adrenal gland, myocardium, lung, eye and choroid plexus). The presence of the parasite was confirmed with a specific immunocytochemical stain. The possibility of an immunological aetiology of the vasculitis and its classification is discussed.
描述了两例与系统性坏死性血管炎相关的犬利什曼病。主要宏观病变为出血性；组织病理学变化证实血管病变累及多个器官的小动脉（皮肤、肠道、肾脏、膀胱、肠系膜淋巴结、肾上腺、心肌、肺、眼和脉络丛）。通过特异性免疫细胞化学染色证实了寄生虫的存在。讨论了血管炎的免疫病因及其分类的可能性。
