Cowley Alice, Dobson Laura, Kurian John, Saunderson Christopher
Department of Cardiology, Leeds General Infirmary, Leeds, UK.
Department of Cardiology, Bradford Royal Infirmary, Bradford, UK.
Echo Res Pract. 2017 Sep;4(3):K25-K29. doi: 10.1530/ERP-17-0024. Epub 2017 Aug 16.
Isolated myocardial involvement in tuberculosis is exceedingly rare but there are reports it can present with sudden cardiac death, atrioventricular block, ventricular arrhythmias or congestive cardiac failure. We report the case of a 33-year-old male, of South Asian descent, who presented with chest pain, shortness of breath and an abnormal ECG. The patient had no significant past medical history and coronary angiogram showed no evidence of coronary artery disease. Of note, the patient had recently been discharged from a local district hospital with an episode of myocarditis. The patient was found to be severely hypoxic with evidence of severe biventricular failure on echocardiography. Computed tomography of the chest demonstrated hilar lymphadenopathy, and the differential diagnosis was thought to be tuberculosis or sarcoidosis. A TB Quantiferon gold test performed at the district hospital was positive; however, fine needle aspiration was negative for acid-fast bacilli. Despite aggressive diuresis, the patient became increasingly hypoxic and suffered a cardiac arrest. Post-mortem confirmed a diagnosis of myocardial tuberculosis - a rare case of acute decompensated heart failure.
Tuberculosis myocarditis is a rare diagnosis but should be considered in at risk individuals presenting with acute fulminant myocarditis.Cardiac failure can occur even in the absence of disseminated tubercular disease.TB myocarditis is not just a disease of the immunocompromised.Definitive diagnosis of cardiac tuberculosis during life requires a myocardial biopsy.Echocardiography is a vital tool for the assessment of cardiac function, filling pressures and fluid status in the critically unwell patient.
孤立性心肌结核极为罕见,但有报道称其可表现为心源性猝死、房室传导阻滞、室性心律失常或充血性心力衰竭。我们报告一例33岁南亚裔男性病例,该患者出现胸痛、呼吸急促及心电图异常。患者既往无重大病史,冠状动脉造影未显示冠状动脉疾病证据。值得注意的是,该患者近期因心肌炎发作从当地一家区级医院出院。经超声心动图检查发现患者严重缺氧,并有严重双心室衰竭迹象。胸部计算机断层扫描显示肺门淋巴结肿大,鉴别诊断考虑为结核病或结节病。在区级医院进行的结核菌素金标试验呈阳性;然而,细针穿刺未发现抗酸杆菌。尽管积极利尿,患者缺氧情况仍日益加重并发生心脏骤停。尸检确诊为心肌结核——一例罕见的急性失代偿性心力衰竭病例。
结核性心肌炎是一种罕见诊断,但对于出现急性暴发性心肌炎的高危个体应予以考虑。即使在无播散性结核疾病的情况下也可能发生心力衰竭。结核性心肌炎不仅仅是免疫功能低下者的疾病。生前确诊心脏结核需要进行心肌活检。超声心动图是评估危重症患者心脏功能、充盈压和液体状态的重要工具。