Ristau E, Roessler H, Burkardt H, Scholz D, Rosenthal S
Acta Virol. 1986 Nov;30(6):449-56.
Plasma membranes of cells from lymph nodes of bovine leukaemia virus (BLV)-free cattle and of cells from tumorous lymph nodes of BLV-infected cattle have been investigated for their reactivity with iodine labelled BLV antigens gp51 and p24. It has been found that only the plasma membranes from cells of tumorous lymph nodes bound gp51 and p24. The binding could be abolished by addition of nonlabelled antigens. It has been calculated from Scatchard plot analysis that 10(5) molecules of gp51 or 10(4) molecules of p24 can be bound per tumour cell. The findings led to the conclusion that tumour cells of BLV-infected cattle are endowed with receptors for the BLV antigens gp51 and p24.
对来自未感染牛白血病病毒（BLV）的牛的淋巴结细胞以及来自感染BLV的牛的肿瘤性淋巴结细胞的质膜，研究了它们与碘标记的BLV抗原gp51和p24的反应性。已发现只有来自肿瘤性淋巴结细胞的质膜能结合gp51和p24。加入未标记的抗原可消除这种结合。通过Scatchard图分析计算得出，每个肿瘤细胞可结合10⁵个gp51分子或10⁴个p24分子。这些发现得出结论，感染BLV的牛的肿瘤细胞具有BLV抗原gp51和p24的受体。
