Dambrain R, Barrellier P, Billet J, Lecacheux B
Rev Stomatol Chir Maxillofac. 1979;80(3):140-5.
Fragments of the lower jaw from 42 patients with carcinoma of the oral cavity or oropharynx, and treated primarely with fraction radiotherapy, were excised for radiation osteonecrosis 6 month to 10 years after irradiations. The excised specimens are X-rayed before being coated with methylmetacrylate. They are then cut into thick sections along lines detailled on the X-ray films. The sections are trimmed to 80 microns and examined microradiographically. Two observations are sufficient to demonstrate destruction or reorganisation of the bone tissue. Reabsorption of unusual appearance is seen around the Haversian canals. The newly formed tissue resembles either embryonic bone matter, or lamellar tissue as seen in osteomyelitis.
42例口腔或口咽癌患者,主要接受分次放射治疗,放疗后6个月至10年,因放射性骨坏死切除下颌骨碎片。切除的标本在涂覆甲基丙烯酸甲酯之前进行X线检查。然后沿着X线片上详细标注的线切成厚切片。将切片修整至80微米并进行显微放射照相检查。两项观察结果足以证明骨组织的破坏或重组。在哈弗斯管周围可见外观异常的重吸收。新形成的组织类似于胚胎骨物质或骨髓炎中所见的板层组织。