Shores Molly M
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, VA Puget Sound Health Care System, 1660 South Columbian Way Seattle, WA 98108, USA.
Asian J Androl. 2018 Mar-Apr;20(2):138-144. doi: 10.4103/aja.aja_25_17.
Over the past decade, there has been a substantial increase in the number of men who are treated with testosterone. Despite this increase in the use of testosterone, the risks of adverse cardiovascular events are unclear as meta-analyses have reported conflicting findings and no clinical studies have been large enough or long enough to adequately assess for cardiovascular risks. The goal of this paper is to review large prescription database studies of testosterone treatment and adverse cardiovascular events and mortality with the aim of providing some guidance for clinicians and researchers in this controversial area.
在过去十年中,接受睾酮治疗的男性人数大幅增加。尽管睾酮的使用有所增加,但不良心血管事件的风险尚不清楚,因为荟萃分析报告的结果相互矛盾,而且没有足够大或足够长的临床研究来充分评估心血管风险。本文的目的是回顾关于睾酮治疗以及不良心血管事件和死亡率的大型处方数据库研究,旨在为这一有争议领域的临床医生和研究人员提供一些指导。