Rajasekaran Shanmuganathan, Kanna Rishi M, Schnake Klaus J, Vaccaro Alexander R, Schroeder Gregory D, Sadiqi Said, Oner Cumhur
*Department of Orthopaedics, Trauma and Spine Surgery, Ganga Hospital, Coimbatore, India; †Center for Spine and Scoliosis Surgery, Schön Klinik Nürnberg Fürth, Fürth, Germany; ‡Department of Orthopaedic Surgery, The Rothman Institute, Thomas Jefferson University, Philadelphia, PA, USA; and §Department of Orthopaedics, University Medical Center Utrecht, Utrecht, the Netherlands.
J Orthop Trauma. 2017 Sep;31 Suppl 4:S49-S56. doi: 10.1097/BOT.0000000000000949.
Osteoporotic vertebral fractures constitute at least 50% of the osteoporotic fractures that happen worldwide. Occurrence of osteoporotic fractures make the elderly patient susceptible for further fractures and increases the morbidity due to kyphosis and pain; the mortality risk is also increased in these patients. Most fractures occur in the thoracic and thoracolumbar region and are often stable. Different descriptive and prognostic classification systems have been described, but none are universally accepted. Radiographs, computed tomography, and magnetic resonance imaging are useful in imaging the fracture and evaluating the bone density. In acute stages, the fractures are well treated with conservative measures including short bed rest, analgesics, bracing, and exercises. Although most fractures heal well, up to 30% of fractures can develop painful nonunion, progressive kyphosis, and neurological deficit. For patients who develop severe pain not responding to nonoperative measures and painful nonunion, percutaneous cement augmentation procedures including vertebroplasty or kyphoplasty have been suggested. For fractures with severe collapse and that lead to neurological deficit and increasing kyphosis, instrumented stabilization is advised. Prevention and management of osteoporosis is the key element in the management of osteoporotic fractures in the elderly. Guidelines for essential adequate dietary and supplemental calcium and vitamin D, and antiosteoporotic medications have been described.
骨质疏松性椎体骨折占全球发生的骨质疏松性骨折的至少50%。骨质疏松性骨折的发生使老年患者易发生进一步骨折,并增加因脊柱后凸和疼痛导致的发病率;这些患者的死亡风险也会增加。大多数骨折发生在胸椎和胸腰段区域,且通常为稳定性骨折。已经描述了不同的描述性和预后分类系统,但没有一个被普遍接受。X线片、计算机断层扫描和磁共振成像在骨折成像和评估骨密度方面很有用。在急性期,骨折通过包括短期卧床休息、镇痛药、支具和锻炼在内的保守措施得到很好的治疗。尽管大多数骨折愈合良好,但高达30%的骨折可发展为疼痛性骨不连、进行性脊柱后凸和神经功能缺损。对于出现对非手术措施无反应的严重疼痛和疼痛性骨不连的患者,已建议采用包括椎体成形术或后凸成形术在内的经皮骨水泥强化手术。对于伴有严重塌陷、导致神经功能缺损和脊柱后凸加重的骨折,建议进行器械固定。骨质疏松症的预防和管理是老年骨质疏松性骨折管理的关键要素。已经描述了关于必需的充足饮食和补充钙及维生素D以及抗骨质疏松药物的指南。