Ghadiyaram Ashwin, Krishnakumar Asha, Leppo Janan, Rajagopal Megan M, Poulos Nora T, Opalak Charles F, Broaddus William C, Cameron Brian M
Department of Neurosurgery, Virginia Commonwealth University Health System, Richmond, USA.
Department of Internal Medicine, University of California San Diego, San Diego, USA.
Cureus. 2024 Aug 7;16(8):e66402. doi: 10.7759/cureus.66402. eCollection 2024 Aug.
Thoracolumbar (TL) junction fractures are common, often resulting from high-energy trauma or osteoporosis, and may lead to neurological deficits, deformities, or chronic pain. Treatment decisions for neurologically intact patients remain controversial, with nonsurgical management often favored. The AO classification system has been used to characterize thoracolumbar fractures using fracture morphology and clinical factors affecting clinical decision-making for fracture management. This study aims to assess the radiographic outcomes of utilizing a thoracolumbosacral orthosis (TLSO) brace in neurologically intact patients with TL fractures based on the AO classification system.
A retrospective analysis of 43 patients was conducted using data from the VCU Spine Database on patients with TL fractures managed conservatively with a TLSO brace from 2010 to 2019. Demographic variables and radiographic measurements of anterior height loss were analyzed and stratified by AO fracture class.
Significant differences were observed in anterior height loss between AO fracture classes, with A4 fractures showing significantly greater anterior height loss at initial presentation (27.6 + 4.8%) compared to A1/A2 (16.1 + 2.2%; p=0.049). At follow up, A4 fractures had a significantly greater anterior height loss (40.2 + 6.6%) than both the A1/A2 (22.4 + 2.9%; p=0.029) and A3 fracture classes (20.5 + 3.6; p=0.020).
The study highlights significant differences in anterior height loss among AO fracture classes, suggesting varying degrees of severity and potential implications for clinical management. While conservative treatment with TLSO braces may provide pain relief, surgical intervention may offer better structural recovery, especially in more severe fractures. Conservative management of TL fractures with TLSO braces may result in greater anterior height loss, particularly in A4 fractures, emphasizing the need for individualized treatment decisions. Further research, including prospective studies, is warranted to validate these findings and guide clinical practice effectively.
胸腰段(TL)交界区骨折很常见,通常由高能创伤或骨质疏松引起,可能导致神经功能缺损、畸形或慢性疼痛。对于神经功能完好的患者,治疗决策仍存在争议,非手术治疗往往更受青睐。AO分类系统已被用于根据骨折形态和影响骨折治疗临床决策的临床因素来描述胸腰段骨折。本研究旨在基于AO分类系统评估在神经功能完好的TL骨折患者中使用胸腰骶矫形器(TLSO)支具的影像学结果。
使用弗吉尼亚联邦大学脊柱数据库中2010年至2019年采用TLSO支具保守治疗的TL骨折患者的数据,对43例患者进行回顾性分析。分析人口统计学变量和前柱高度丢失的影像学测量结果,并按AO骨折类型进行分层。
在AO骨折类型之间观察到前柱高度丢失存在显著差异,A4骨折在初次就诊时的前柱高度丢失(27.6 + 4.8%)明显大于A1/A2骨折(16.1 + 2.2%;p = 0.049)。在随访时,A4骨折的前柱高度丢失(40.2 + 6.6%)明显大于A1/A2骨折(22.4 + 2.9%;p = 0.029)和A3骨折类型(20.5 + 3.6;p = 0.020)。
该研究突出了AO骨折类型之间在前柱高度丢失方面的显著差异,表明严重程度不同以及对临床治疗的潜在影响。虽然使用TLSO支具进行保守治疗可能缓解疼痛,但手术干预可能提供更好的结构恢复,尤其是在更严重的骨折中。使用TLSO支具对TL骨折进行保守治疗可能导致更大的前柱高度丢失,特别是在A4骨折中,强调了需要进行个体化治疗决策。有必要进行进一步的研究,包括前瞻性研究,以验证这些发现并有效地指导临床实践。