Animal Genetics and Nutrition, Veterinary Sciences Discipline, College of Public Health, Medical and Veterinary Sciences, Division of Tropical Health and Medicine, James Cook University, Townsville, QLD 4811, Australia.
National Institute of Animal Science, Thuy Phuong, Bac Tu Liem, Hanoi 129909, Vietnam.
Nutrients. 2017 Aug 17;9(8):893. doi: 10.3390/nu9080893.
The objective of the study was to ascertain whether human health beneficial omega-3 long-chain (≥C) polyunsaturated fatty acid (-3 LC-PUFA) content in heart, kidney and liver can be enhanced by supplementing prime lambs with graded levels of canola and flaxseed oil. Health status of the lambs, as a consequence of the supplementation, was also investigated by examining their plasma metabolites. Sixty purebred and first-cross lambs were allocated to one of five treatments of lucerne hay basal diet supplemented with isocaloric and isonitrogenous wheat-based pellets without oil inclusion (Control) or graded levels of canola oil at 2.5% (2.5C), 5% (5C), flaxseed oil at 2.5% (2.5F) and 5% (5F) in a completely randomised design. Pre-slaughter blood, post-slaughter kidney, liver and heart samples were analysed for plasma metabolite and fatty acid profiles. Summations of docosapentaenoic acid and docosahexaenoic acid, and total -3 LC-PUFA were enhanced in the liver and kidney of 5F supplemented lambs with a marked decrease in -6/-3 ratio and significant breed differences detected. There were generally no deleterious impacts on animal health status. A combination of 5% oil supplementation and lamb genetics is an effective and strategic management tool for enhancing -3 LC-PUFA contents of heart, kidney and liver without compromising lamb health.
本研究旨在确定通过在育肥羔羊饲料中添加不同水平的菜籽油和亚麻籽油，是否可以提高心、肾和肝组织中对人类健康有益的 ω-3 长链（≥C）多不饱和脂肪酸（-3 LC-PUFA）的含量。本研究还通过检测羔羊的血浆代谢物，研究了补充这些油对羔羊健康状况的影响。将 60 只纯种和第一代杂交羔羊随机分为 5 个处理组，每组 12 只，分别饲喂基础紫花苜蓿干草日粮和添加等热量和等氮量的不含油的小麦基颗粒饲料（对照组），或添加 2.5%（2.5C）、5%（5C）菜籽油、2.5%（2.5F）和 5%（5F）亚麻籽油。在屠宰前采集血液，屠宰后采集肾脏、肝脏和心脏样本，分析血浆代谢物和脂肪酸谱。结果表明，5F 组羔羊的肝脏和肾脏中的二十二碳五烯酸和二十二碳六烯酸以及总 -3 LC-PUFA 的含量增加，ω-6/ω-3 比例显著降低，且不同品种之间存在显著差异。此外，一般情况下，这种添加油的方式对动物的健康状况没有不良影响。综合考虑 5%的油添加水平和羔羊的遗传因素，是一种有效且具有战略意义的管理工具，可以在不损害羔羊健康的情况下提高心、肾和肝组织中 -3 LC-PUFA 的含量。
