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氟烷对椎实螺摄食运动活动的影响。

Effects of halothane on feeding motor activity in the snail Lymnaea stagnalis.

作者信息

McCrohan C R, Girdlestone D, Winlow W

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987;86(1):55-62. doi: 10.1016/0742-8413(87)90144-7.

DOI:10.1016/0742-8413(87)90144-7
PMID:2881727
Abstract

Snails exposed to the general anaesthetic halothane show an increase in biting plus mouthing movements. Perfusion of the isolated CNS with halothane leads to a period of increased spiking activity, followed by suppression of activity in identified feeding motoneurones in the buccal ganglia. Synaptic inputs to motoneurones from interneurones of the buccal feeding pattern generator are differentially affected. Possible mechanisms underlying the generation of motoneuronal bursting in the presence of halothane are examined.

摘要

暴露于全身麻醉药氟烷的蜗牛咬和口部动作增加。用氟烷灌注离体中枢神经系统会导致一段时间的放电活动增加,随后颊神经节中已确定的摄食运动神经元的活动受到抑制。来自颊部摄食模式发生器中间神经元的运动神经元突触输入受到不同影响。研究了在氟烷存在下运动神经元爆发产生的可能机制。

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引用本文的文献

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A Comparative Study of Cell Specific Effects of Systemic and Volatile Anesthetics on Identified Motor Neurons and Interneurons of (L.), Both in the Isolated Brain and in Single Cell Culture.全身麻醉药和挥发性麻醉药对(某种生物)已鉴定的运动神经元和中间神经元的细胞特异性作用的比较研究,在离体脑和单细胞培养中均有涉及。 (注:原文中括号里的“(L.)”指代不明,需根据具体背景确定准确内容)
Front Physiol. 2019 May 31;10:583. doi: 10.3389/fphys.2019.00583. eCollection 2019.
2
Sense and Insensibility - An Appraisal of the Effects of Clinical Anesthetics on Gastropod and Cephalopod Molluscs as a Step to Improved Welfare of Cephalopods.《感知与无感知——评估临床麻醉剂对腹足纲和头足纲软体动物的影响,迈向改善头足纲动物福利的一步》
Front Physiol. 2018 Aug 24;9:1147. doi: 10.3389/fphys.2018.01147. eCollection 2018.
3
Mechanisms of Anesthetic Action and Neurotoxicity: Lessons from Molluscs.麻醉作用机制与神经毒性:来自软体动物的启示。
Front Physiol. 2018 Jan 23;8:1138. doi: 10.3389/fphys.2017.01138. eCollection 2017.