McCrohan C R, Girdlestone D, Winlow W
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987;86(1):55-62. doi: 10.1016/0742-8413(87)90144-7.
Snails exposed to the general anaesthetic halothane show an increase in biting plus mouthing movements. Perfusion of the isolated CNS with halothane leads to a period of increased spiking activity, followed by suppression of activity in identified feeding motoneurones in the buccal ganglia. Synaptic inputs to motoneurones from interneurones of the buccal feeding pattern generator are differentially affected. Possible mechanisms underlying the generation of motoneuronal bursting in the presence of halothane are examined.
暴露于全身麻醉药氟烷的蜗牛咬和口部动作增加。用氟烷灌注离体中枢神经系统会导致一段时间的放电活动增加,随后颊神经节中已确定的摄食运动神经元的活动受到抑制。来自颊部摄食模式发生器中间神经元的运动神经元突触输入受到不同影响。研究了在氟烷存在下运动神经元爆发产生的可能机制。