一名12岁女孩以抗利尿激素分泌异常综合征为首发表现，该综合征是未成熟卵巢畸胎瘤的初始表现，实属罕见。
A Rare Presentation of the Syndrome of Inappropriate Antidiuretic Hormone in a 12-Year-Old Girl as the Initial Presentation of an Immature Ovarian Teratoma.
作者信息
Iqbal Anoop Mohamed, Schwenk W Frederick
机构信息
Division of Pediatric Endocrinology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota.
Division of Pediatric Endocrinology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota.
出版信息
J Pediatr Adolesc Gynecol. 2018 Feb;31(1):62-63. doi: 10.1016/j.jpag.2017.08.002. Epub 2017 Aug 14.
BACKGROUND
Immature ovarian teratoma is very rare in childhood. We report on a 12-year-old girl with immature ovarian teratoma who presented initially with syndrome of inappropriate antidiuretic hormone.
CASE
A 12-year-old girl presented with acute abdomen and distention. Initial laboratory tests showed hyponatremia (sodium, 123 mmol/L), that did not respond to fluid management. Computed tomography imaging showed a 15 cm × 9 cm × 20 cm mass in the right ovary with multifocal internal fat, and dystrophic calcifications. She underwent exploratory laparotomy with a right salpingo-oophorectomy, omentectomy, and peritoneal stripping. The pathology revealed metastatic immature teratoma. Hyponatremia resolved soon after the surgery.
SUMMARY AND CONCLUSION
Although a rare diagnosis, immature ovarian teratoma must be considered in a girl who presents with abdominal mass and hyponatremia.
背景
儿童期未成熟卵巢畸胎瘤非常罕见。我们报告一例12岁患有未成熟卵巢畸胎瘤的女孩，其最初表现为抗利尿激素分泌异常综合征。
病例
一名12岁女孩出现急腹症和腹胀。初始实验室检查显示低钠血症（血钠123 mmol/L），经液体管理无改善。计算机断层扫描成像显示右卵巢有一个15 cm×9 cm×20 cm的肿块，内部有多灶性脂肪及营养不良性钙化。她接受了剖腹探查术，并行右侧输卵管卵巢切除术、大网膜切除术和腹膜剥除术。病理显示为转移性未成熟畸胎瘤。术后低钠血症很快得到缓解。
总结与结论
尽管诊断罕见，但对于出现腹部肿块和低钠血症的女孩，必须考虑未成熟卵巢畸胎瘤的可能。
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