Gibbs R A, Camakaris J, Hodgson G S, Martin R F
Int J Radiat Biol Relat Stud Phys Chem Med. 1987 Feb;51(2):193-9. doi: 10.1080/09553008714550691.
The predominant initial lesion induced by 125I decay in DNa is a double-strand DNA break comprising a 'mini deletion' of up to several base pairs (bp). However, Southern analysis of the structure of 125I decay-induced HPRT mutants in Chinese hamster ovary cells revealed that most of the mutants are deletions of thousands of bps. A similar predominance of substantial deletions was also found in X-ray-induced mutants.
