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[An Adult Case of Enterovirus D68 Encephalomyelitis Presenting as Bilateral Facial Nerve Palsy and Dysphagia].

作者信息

Kusabe Yuta, Takeshima Akari, Seino Azusa, Nishida Mana, Takahashi Mami, Yamada Shota, Shimbo Junsuke, Sato Aki, Okamoto Kouichirou, Igarashi Shuichi

机构信息

Department of Neurology, Niigata City General Hospital.

出版信息

Brain Nerve. 2017 Aug;69(8):957-961. doi: 10.11477/mf.1416200848.

DOI:10.11477/mf.1416200848
PMID:28819079
Abstract

A 33-year-old man was admitted to our hospital with bilateral facial nerve paralysis, dysphagia, and muscle weakness in the neck and trunk following fever, headache and throat pain. T-weighted brain magnetic resonance imaging (MRI) showed hyperintense lesions in the tegmentum of the brain stem and the ventral region of the superior cervical cord. Based on the characteristic findings on the brain MRI, we diagnosed the patient with enteroviral encephalomyelitis. Steroid therapy was administered; however, his bilateral facial nerve paralysis and dysphagia were refractory to this therapy. Subsequently, enterovirus D68 was detected in the serum using polymerase chain reaction (PCR) analysis. At that time, an outbreak of enteroviral D68 infection was reported in Japan. Finally, we diagnosed encephalomyelitis caused by enteroviral D68 infection. Characteristic MRI findings were very useful in narrowing down the differential diagnosis in this patient. (Received March 3, 2017; Accepted April 20, 2017; Published August 1, 2017).

摘要

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1
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引用本文的文献

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Enterovirus-D68 - A Reemerging Non-Polio Enterovirus that Causes Severe Respiratory and Neurological Disease in Children.肠道病毒D68型——一种再度出现的非脊髓灰质炎肠道病毒,可导致儿童严重呼吸道和神经系统疾病。
Front Virol. 2024;4. doi: 10.3389/fviro.2024.1328457. Epub 2024 Feb 14.
2
Human B cells and dendritic cells are susceptible and permissive to enterovirus D68 infection.人 B 细胞和树突状细胞易感染肠道病毒 D68 并对其具有感染性和容纳性。
mSphere. 2024 Feb 28;9(2):e0052623. doi: 10.1128/msphere.00526-23. Epub 2024 Jan 23.
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The pathogenesis and virulence of enterovirus-D68 infection.
肠道病毒 D68 感染的发病机制和毒力。
Virulence. 2021 Dec;12(1):2060-2072. doi: 10.1080/21505594.2021.1960106.