Reich J, Chaudry D
J Nerv Ment Dis. 1987 Apr;175(4):224-8. doi: 10.1097/00005053-198704000-00006.
Seventeen (28%) of 61 panic disorder patients in a drug treatment study were retrospectively found to have a history of alcoholism (none had abused alcohol in the past year), More men than women had a history of alcohol abuse (p less than .03). Alcohol patients were less independent and less able to recognize appropriate social cues on personality testing. There was significant improvement in general anxiety for the drug treatment and nonalcoholic placebo group but not for the alcohol placebo group. This indicates a superior response to supportive therapy for general anxiety in the placebo group without an alcohol abuse history compared with the placebo group with an alcohol abuse history.
在一项药物治疗研究中，61名恐慌症患者中有17名（28%）经回顾性研究发现有酗酒史（过去一年中无人酗酒）。有酗酒史的男性多于女性（p值小于0.03）。在人格测试中，有酗酒问题的患者独立性较差，识别适当社交线索的能力也较弱。药物治疗组和无酒精滥用史的安慰剂组的一般焦虑症状有显著改善，但有酒精滥用史的安慰剂组则没有。这表明，与有酒精滥用史的安慰剂组相比，无酒精滥用史的安慰剂组对支持性治疗的一般焦虑反应更佳。
