Mellman T A, Uhde T W
Unit on Anxiety and Affective Disorders, NIMH, Bethesda, MD 20892.
Am J Psychiatry. 1987 Dec;144(12):1573-6. doi: 10.1176/ajp.144.12.1573.
Previous reports have noted an increased prevalence of obsessive-compulsive symptoms in patients with panic disorder. The authors found a prevalence of obsessive-compulsive symptoms in 19 (27%) of 70 patients with panic disorder. Compared to a subgroup of 25 patients with classic features of panic disorder and no obsessive-compulsive symptoms, the subgroup with obsessive-compulsive symptoms had an earlier onset of illness, were more likely to have personal and family histories of major depression and substance abuse, and showed a poorer outcome after treatment.
先前的报告指出，恐慌症患者中强迫症状的患病率有所增加。作者发现，70名恐慌症患者中有19名（27%）存在强迫症状。与25名具有恐慌症典型特征且无强迫症状的患者亚组相比，有强迫症状的亚组发病更早，更有可能有重度抑郁和物质滥用的个人及家族病史，且治疗后的结果更差。
