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炎症性肠病与妊娠

Inflammatory bowel disease and pregnancy.

作者信息

Maliszewska Anna Małgorzata, Warska Aleksandra, Cendrowski Krzysztof, Sawicki Włodzimierz

机构信息

Chair and Clinic of Obstetrics, Gynecology and Oncology, Second Faculty of Medicine, Medical University of Warsaw, Poland, Kondratowicza St.8, 03-242, Warsaw, Poland.

出版信息

Ginekol Pol. 2017;88(7):398-403. doi: 10.5603/GP.a2017.0074.

Abstract

Inflammatory bowel disease (IBD) comprising Crohn's disease (CD), ulcerative colitis (UC), and IBD-unclassified (IBD-U) may appear at any age. As such, IBD commonly affects young patients in their reproductive age. Rate of voluntary childlessness among women with IBD far exceed that of the general population, as patients with IBD fear not only the effect of pregnancy on the course of inflammatory bowel disease, but also the increased risk of the offspring developing the disease, adverse pregnancy outcomes, the effect IBD treatment may have on the health and development of the infant or the risk of relapse during pregnancy and the influence of lactation on child development and disease course. This article aims at improving pre-conception counseling of patients with inflammatory bowel disease.

摘要

炎症性肠病(IBD)包括克罗恩病(CD)、溃疡性结肠炎(UC)和未分类的IBD(IBD-U),可在任何年龄出现。因此,IBD通常影响育龄期的年轻患者。IBD女性的自愿不育率远高于普通人群,因为IBD患者不仅担心怀孕对炎症性肠病病程的影响,还担心后代患该病的风险增加、不良妊娠结局、IBD治疗可能对婴儿健康和发育产生的影响、怀孕期间复发的风险以及哺乳对儿童发育和疾病病程的影响。本文旨在改善炎症性肠病患者的孕前咨询。

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